The Runx3 Transcription Factor Augments Th1 and Down-Modulates Th2 Phenotypes by Interacting with and Attenuating GATA3

Recently, it was reported that the expression of Runt-related transcription factor 3 (Runx3) is up-regulated in CD4+ helper T cells during Th1 cell differentiation, and that Runx3 functions in a positive feed-forward manner with the T-box family transcription factor, T-bet, which is a master regulat...

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Bibliographic Details
Main Authors: Kohu, K., Ohmori, H., Wong, W.F., Onda, D., Wakoh, T., Kon, S., Yamashita, M., Nakayama, T., Kubo, M., Satake, M.
Format: Article
Published: American Association of Immunologists 2009
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Online Access:http://eprints.um.edu.my/13021/
http://www.jimmunol.org/content/183/12/7817.full
http://dx.doi.org/10.4049/​jimmunol.0802527
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