Childhood adrenocortical carcinoma as a sentinel cancer for detecting families with germline TP53 mutations
Li-Fraumeni syndrome (LFS) is a highly penetrant, autosomal dominant disorder where affected individuals carry a 50% risk of developing cancer before 30 years of age. It is most commonly associated with mutations in the tumour suppressor gene, TP53. Adrenocortical carcinoma (ACC) is a very rare paed...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Wiley
2012
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/10499/1/00000727_80283.pdf http://eprints.um.edu.my/10499/ |
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