Virtual Screening, Synthesis, and Biological Evaluation of Some Carbohydrazide Derivatives as Potential DPP-IV Inhibitors

Dipeptidyl peptidase-4 (DPP-IV) inhibitors are known as safe and well-tolerated antidiabetic medicine. Therefore, the aim of the present work was to synthesize some carbohydrazide derivatives (1a–5d) as DPP-IV inhibitors. In addition, this work involves simulations using molecular docking, ADMET ana...

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Main Authors:	Jadhav, Prerana B., Jadhav, Shailaja B., Zehravi, Mehrukh, Mubarak, Mohammad S., Islam, Fahadul, Jeandet, Philippe, Khan, Sharuk L., Hossain, Nazmul, Rashid, Salma, Long, Chiau Ming *, Sarker, Md. Moklesur Rahman, Mohd Fahami, Nur Azlina
Format:	Article
Language:	en
Published:	MDPI 2023
Subjects:	QP Physiology QR Microbiology RC Internal medicine
Online Access:	http://eprints.sunway.edu.my/2790/1/Long%20Chiau%20Ming_Virtual%20screening%20synthesis%20and%20biological%20evaluation.pdf http://eprints.sunway.edu.my/2790/ https://doi.org/10.3390/molecules28010149
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