QSAR modelling to predict structural features of certain sulfonamide as Urokinase-type Plasminogen Activator inhibitors

The serine hydrolase family includes serine proteases. It is essential for hydrolyzing protein peptide bonds and breaking them. The urokinase-type plasminogen activator (uPA) selectively binds to the uPAR on numerous cell types, including cancer cells. Pericellular proteolysis of cell-bound proteins...

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Bibliographic Details

Main Authors:	Jawarkar, Rahul D, Zaki, Magdi E A, Al-Hussain, Sami, Alzahrani, Abdullah Yahya Abdullah, Long, Chiau Ming *, Samad, Abdul, Ingle, Rahul G., Mali, Suraj N.
Format:	Article
Published:	Elsevier 2024
Subjects:	QP Physiology RM Therapeutics. Pharmacology
Online Access:	http://eprints.sunway.edu.my/2611/ https://doi.org/10.1016/j.chphi.2024.100544
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