Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

Background: Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients, and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibioti...

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Main Authors:	Zhu, Yan, Czauderna, Tobias, Zhao, Jinxin, Klapperstueck, Matthias, Maifiah, Mohd Hafidz Mahamad, Han, Mei-Ling, Lu, Jing, Sommer, Björn, Velkov, Tony, Lithgow, Trevor, Song, Jiangning, Schreiber, Falk, Li, Jian
Format:	Article
Language:	en
Published:	Oxford Academic 2018
Subjects:	QR Microbiology RM Therapeutics. Pharmacology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/65380/1/2018_giy021.pdf http://irep.iium.edu.my/65380/ https://academic.oup.com/gigascience/article/7/4/giy021/4931736?searchresult=1
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