Mechanistic insights into the sleep-glymphopathy-cerebral small vessel disease loop: implications for epilepsy pathophysiology and therapy

Epilepsy is the second most common neurological disorder and affects approximately 50 million people worldwide. Despite advances in antiepileptic therapy, about 30% of patients develop refractory epilepsy. Recent studies have shown sleep, glymphatic function, cerebral small vessel disease (CSVD), an...

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Main Authors: Hein, Zaw Myo, al-Zaghal, Zaid Adnan Subhi, Mohammad Ghazali, Mazira, Jaffer, Usman, Abdul Hamid, Hafizah, Mehat, Muhammad Zulfadli, Che Ramli, Muhammad Danial, Che Mohd Nassir, Che Mohd Nasril
Format: Article
Language:en
en
Published: Frontiers Media SA 2025
Subjects:
Online Access:http://irep.iium.edu.my/122512/7/122512_Mechanistic%20insights%20into%20the%20sleep.pdf
http://irep.iium.edu.my/122512/8/122512_Mechanistic%20insights%20into%20the%20sleep_Scopus.pdf
http://irep.iium.edu.my/122512/
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1546482/full
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