The NLRP3 inflammasome in age-related cerebral small vessel disease manifestations: untying the innate immune response connection

In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSV...

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Bibliographic Details

Main Authors:	Che Mohd Nassir, Che Mohd Nasril, Damodaran, Thenmoly, Ismail, Nurul Iman, Hashim, Sabarisah, Jaffer, Usman, Abdul Hamid, Hafizah, Mehat, Muhammad Zulfadli, Norazit, Anwar, Mustapha, Muzaimi
Format:	Article
Language:	en en
Published:	Multidisciplinary Digital Publishing Institute (MDPI) 2023
Subjects:	RC321 Neuroscience. Biological psychiatry. Neuropsychiatry RC633 Specialties of Internal Medicines- Diseases of The Blood and Blood-forming Organs. Hematologic Diseases RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
Online Access:	http://irep.iium.edu.my/103207/8/103207_The%20NLRP3%20inflammasome%20in%20age-related%20cerebral_SCOPUS.pdf http://irep.iium.edu.my/103207/9/103207_The%20NLRP3%20inflammasome%20in%20age-related%20cerebral.pdf http://irep.iium.edu.my/103207/ https://www.mdpi.com/2075-1729/13/1/216
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