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Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia

Since 2000, human malaria cases in Malaysia were rapidly reduced with the use of insecticides in Indoor Residual Spray (IRS) and Long-Lasting Insecticide Net (LLIN). Unfortunately, monkey malaria in humans has shown an increase especially in Sabah and Sarawak. The insecticide currently used in IRS i...

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Main Authors: Ahmed, Md Atique, Rohani, A., Fakhriy, H. Ahmad, Suzilah, I., Zurainee, M. N., W. M. A., Wan Nadjah, Ariffin, M. Mohd, Shakirudin, N. Mohamad, M. S., Mohd Afiq, Jenarun, J., Tanrang, Y., Lee, H. L.
Format: Article
Language:English
Published: 2020
Subjects:
QA75 Electronic computers. Computer science
Online Access:http://repo.uum.edu.my/27186/1/PO%2015%205%202020%201%2018.pdf
http://repo.uum.edu.my/27186/
http://doi.org/10.1371/journal.pone.0230860
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spelling my.uum.repo.271862020-07-09T06:12:52Z http://repo.uum.edu.my/27186/ Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia Ahmed, Md Atique Rohani, A. Fakhriy, H. Ahmad Suzilah, I. Zurainee, M. N. W. M. A., Wan Nadjah Ariffin, M. Mohd Shakirudin, N. Mohamad M. S., Mohd Afiq Jenarun, J. Tanrang, Y. Lee, H. L. QA75 Electronic computers. Computer science Since 2000, human malaria cases in Malaysia were rapidly reduced with the use of insecticides in Indoor Residual Spray (IRS) and Long-Lasting Insecticide Net (LLIN). Unfortunately, monkey malaria in humans has shown an increase especially in Sabah and Sarawak. The insecticide currently used in IRS is deltamethrin K-Othrine® WG 250 wettable granule, targeting mosquitoes that rest and feed indoor. In Sabah, the primary vector for knowlesi malaria is An. balabacensis a species known to bite outdoor. This study evaluates an alternative method, the Outdoor Residual Spray (ORS) using a novel formulation of deltamethrin K-Othrine® (PolyZone) to examine it suitability to control knowlesi malaria vector in Sabah, compared to the current method. The study was performed at seven villages in Sabah having similar type of houses (wood, bamboo and concrete). Houses were sprayed with deltamethrin K-Othrine® (PolyZone) at two different dosages, 25 mg/m2 and 30 mg/m2 and deltamethrin K-Othrine® WG 250 wettable granule at 25 mg/m2, sprayed indoor and outdoor. Residual activity on different walls was assessed using standard cone bioassay techniques. For larval surveillances, potential breeding sites were surveyed. Larvae were collected and identified, pre and post spraying. Adult survey was done using Human Landing Catch (HLC) performed outdoor and indoor. Detection of malaria parasite in adults was conducted via microscopy and molecular methods. Deltamethrin K-Othrine® (PolyZone) showed higher efficacy when sprayed outdoor. The efficacy was found varied when sprayed on different types of wall surfaces. Deltamethrin K-Othrine® (PolyZone) at 25 mg/m2 was the most effective with regards to ability to high mortality and effective knock down (KD). The vector population was reduced significantly post-spraying and reduction in breeding sites as well. The number of simian malaria infected vector, human and simian malaria transmission were also greatly reduced. 2020 Article PeerReviewed application/pdf en http://repo.uum.edu.my/27186/1/PO%2015%205%202020%201%2018.pdf Ahmed, Md Atique and Rohani, A. and Fakhriy, H. Ahmad and Suzilah, I. and Zurainee, M. N. and W. M. A., Wan Nadjah and Ariffin, M. Mohd and Shakirudin, N. Mohamad and M. S., Mohd Afiq and Jenarun, J. and Tanrang, Y. and Lee, H. L. (2020) Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia. PLOS ONE, 15 (5). pp. 1-18. ISSN 1932-6203 http://doi.org/10.1371/journal.pone.0230860 doi:10.1371/journal.pone.0230860
institution Universiti Utara Malaysia
building UUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Utara Malaysia
content_source UUM Institutional Repository
url_provider http://repo.uum.edu.my/
language English
topic QA75 Electronic computers. Computer science
spellingShingle QA75 Electronic computers. Computer science
Ahmed, Md Atique
Rohani, A.
Fakhriy, H. Ahmad
Suzilah, I.
Zurainee, M. N.
W. M. A., Wan Nadjah
Ariffin, M. Mohd
Shakirudin, N. Mohamad
M. S., Mohd Afiq
Jenarun, J.
Tanrang, Y.
Lee, H. L.
Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
description Since 2000, human malaria cases in Malaysia were rapidly reduced with the use of insecticides in Indoor Residual Spray (IRS) and Long-Lasting Insecticide Net (LLIN). Unfortunately, monkey malaria in humans has shown an increase especially in Sabah and Sarawak. The insecticide currently used in IRS is deltamethrin K-Othrine® WG 250 wettable granule, targeting mosquitoes that rest and feed indoor. In Sabah, the primary vector for knowlesi malaria is An. balabacensis a species known to bite outdoor. This study evaluates an alternative method, the Outdoor Residual Spray (ORS) using a novel formulation of deltamethrin K-Othrine® (PolyZone) to examine it suitability to control knowlesi malaria vector in Sabah, compared to the current method. The study was performed at seven villages in Sabah having similar type of houses (wood, bamboo and concrete). Houses were sprayed with deltamethrin K-Othrine® (PolyZone) at two different dosages, 25 mg/m2 and 30 mg/m2 and deltamethrin K-Othrine® WG 250 wettable granule at 25 mg/m2, sprayed indoor and outdoor. Residual activity on different walls was assessed using standard cone bioassay techniques. For larval surveillances, potential breeding sites were surveyed. Larvae were collected and identified, pre and post spraying. Adult survey was done using Human Landing Catch (HLC) performed outdoor and indoor. Detection of malaria parasite in adults was conducted via microscopy and molecular methods. Deltamethrin K-Othrine® (PolyZone) showed higher efficacy when sprayed outdoor. The efficacy was found varied when sprayed on different types of wall surfaces. Deltamethrin K-Othrine® (PolyZone) at 25 mg/m2 was the most effective with regards to ability to high mortality and effective knock down (KD). The vector population was reduced significantly post-spraying and reduction in breeding sites as well. The number of simian malaria infected vector, human and simian malaria transmission were also greatly reduced.
format Article
author Ahmed, Md Atique
Rohani, A.
Fakhriy, H. Ahmad
Suzilah, I.
Zurainee, M. N.
W. M. A., Wan Nadjah
Ariffin, M. Mohd
Shakirudin, N. Mohamad
M. S., Mohd Afiq
Jenarun, J.
Tanrang, Y.
Lee, H. L.
author_facet Ahmed, Md Atique
Rohani, A.
Fakhriy, H. Ahmad
Suzilah, I.
Zurainee, M. N.
W. M. A., Wan Nadjah
Ariffin, M. Mohd
Shakirudin, N. Mohamad
M. S., Mohd Afiq
Jenarun, J.
Tanrang, Y.
Lee, H. L.
author_sort Ahmed, Md Atique
title Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
title_short Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
title_full Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
title_fullStr Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
title_full_unstemmed Indoor and outdoor residual spraying of a novel formulation of deltamethrin K-Othrine® (Polyzone) for the control of simian malaria in Sabah, Malaysia
title_sort indoor and outdoor residual spraying of a novel formulation of deltamethrin k-othrine® (polyzone) for the control of simian malaria in sabah, malaysia
publishDate 2020
url http://repo.uum.edu.my/27186/1/PO%2015%205%202020%201%2018.pdf
http://repo.uum.edu.my/27186/
http://doi.org/10.1371/journal.pone.0230860
_version_ 1672613159738802176
score 13.211869

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