Cell Engineering and Molecular Pharming for Biopharmaceuticals

Biopharmaceuticals are often produced by recombinant E. coli or mammalian cell lines. This is usually achieved by the introduction of a gene or cDNA coding for the protein of interest into a well-characterized strain of producer cells. Naturally, each recombinant production system has its own uniq...

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Main Author: Abdullah, MA
Format: Citation Index Journal
Published: 2008
Subjects:
Online Access:http://eprints.utp.edu.my/6387/1/49TOMCJ%5B1%5D.pdf
http://eprints.utp.edu.my/6387/
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spelling my.utp.eprints.63872017-01-19T08:26:23Z Cell Engineering and Molecular Pharming for Biopharmaceuticals Abdullah, MA R Medicine (General) Biopharmaceuticals are often produced by recombinant E. coli or mammalian cell lines. This is usually achieved by the introduction of a gene or cDNA coding for the protein of interest into a well-characterized strain of producer cells. Naturally, each recombinant production system has its own unique advantages and disadvantages. This paper examines the current practices, developments, and future trends in the production of biopharmaceuticals. Platform technologies for rapid screening and analyses of biosystems are reviewed. Strategies to improve productivity via metabolic and integrated engineering are also highlighted. 2008 Citation Index Journal PeerReviewed application/pdf http://eprints.utp.edu.my/6387/1/49TOMCJ%5B1%5D.pdf Abdullah, MA (2008) Cell Engineering and Molecular Pharming for Biopharmaceuticals. [Citation Index Journal] http://eprints.utp.edu.my/6387/
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Institutional Repository
url_provider http://eprints.utp.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Abdullah, MA
Cell Engineering and Molecular Pharming for Biopharmaceuticals
description Biopharmaceuticals are often produced by recombinant E. coli or mammalian cell lines. This is usually achieved by the introduction of a gene or cDNA coding for the protein of interest into a well-characterized strain of producer cells. Naturally, each recombinant production system has its own unique advantages and disadvantages. This paper examines the current practices, developments, and future trends in the production of biopharmaceuticals. Platform technologies for rapid screening and analyses of biosystems are reviewed. Strategies to improve productivity via metabolic and integrated engineering are also highlighted.
format Citation Index Journal
author Abdullah, MA
author_facet Abdullah, MA
author_sort Abdullah, MA
title Cell Engineering and Molecular Pharming for Biopharmaceuticals
title_short Cell Engineering and Molecular Pharming for Biopharmaceuticals
title_full Cell Engineering and Molecular Pharming for Biopharmaceuticals
title_fullStr Cell Engineering and Molecular Pharming for Biopharmaceuticals
title_full_unstemmed Cell Engineering and Molecular Pharming for Biopharmaceuticals
title_sort cell engineering and molecular pharming for biopharmaceuticals
publishDate 2008
url http://eprints.utp.edu.my/6387/1/49TOMCJ%5B1%5D.pdf
http://eprints.utp.edu.my/6387/
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