Recent Developments in Metabolomics Studies of Endophytic Fungi
Endophytic fungi are microorganisms that colonize living plants� tissues without causing any harm. They are known as a natural source of bioactive metabolites with diverse pharmacological functions. Many structurally different chemical metabolites were isolated from endophytic fungi. Recently, the...
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my.utp.eprints.336502022-09-07T08:32:33Z Recent Developments in Metabolomics Studies of Endophytic Fungi Nagarajan, K. Ibrahim, B. Bawadikji, A.A. Lim, J.-W. Tong, W.-Y. Leong, C.-R. Khaw, K.Y. Tan, W.-N. Endophytic fungi are microorganisms that colonize living plants� tissues without causing any harm. They are known as a natural source of bioactive metabolites with diverse pharmacological functions. Many structurally different chemical metabolites were isolated from endophytic fungi. Recently, the increasing trends in human health problems and diseases have escalated the search for bioactive metabolites from endophytic fungi. The conventional bioassay-guided study is known as laborious due to chemical complexity. Thus, metabolomics studies have attracted extensive research interest owing to their potential in dealing with a vast number of metabolites. Metabolomics coupled with advanced analytical tools provides a comprehensive insight into systems biology. Despite its wide scientific attention, endophytic fungi metabolomics are relatively unexploited. This review highlights the recent developments in metabolomics studies of endophytic fungi in obtaining the global metabolites picture. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. MDPI 2022 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122325825&doi=10.3390%2fjof8010028&partnerID=40&md5=91153a034f90a0d6ccd2bca218f1adfa Nagarajan, K. and Ibrahim, B. and Bawadikji, A.A. and Lim, J.-W. and Tong, W.-Y. and Leong, C.-R. and Khaw, K.Y. and Tan, W.-N. (2022) Recent Developments in Metabolomics Studies of Endophytic Fungi. Journal of Fungi, 8 (1). http://eprints.utp.edu.my/33650/ |
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Endophytic fungi are microorganisms that colonize living plants� tissues without causing any harm. They are known as a natural source of bioactive metabolites with diverse pharmacological functions. Many structurally different chemical metabolites were isolated from endophytic fungi. Recently, the increasing trends in human health problems and diseases have escalated the search for bioactive metabolites from endophytic fungi. The conventional bioassay-guided study is known as laborious due to chemical complexity. Thus, metabolomics studies have attracted extensive research interest owing to their potential in dealing with a vast number of metabolites. Metabolomics coupled with advanced analytical tools provides a comprehensive insight into systems biology. Despite its wide scientific attention, endophytic fungi metabolomics are relatively unexploited. This review highlights the recent developments in metabolomics studies of endophytic fungi in obtaining the global metabolites picture. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
| format |
Article |
| author |
Nagarajan, K. Ibrahim, B. Bawadikji, A.A. Lim, J.-W. Tong, W.-Y. Leong, C.-R. Khaw, K.Y. Tan, W.-N. |
| spellingShingle |
Nagarajan, K. Ibrahim, B. Bawadikji, A.A. Lim, J.-W. Tong, W.-Y. Leong, C.-R. Khaw, K.Y. Tan, W.-N. Recent Developments in Metabolomics Studies of Endophytic Fungi |
| author_facet |
Nagarajan, K. Ibrahim, B. Bawadikji, A.A. Lim, J.-W. Tong, W.-Y. Leong, C.-R. Khaw, K.Y. Tan, W.-N. |
| author_sort |
Nagarajan, K. |
| title |
Recent Developments in Metabolomics Studies of Endophytic Fungi |
| title_short |
Recent Developments in Metabolomics Studies of Endophytic Fungi |
| title_full |
Recent Developments in Metabolomics Studies of Endophytic Fungi |
| title_fullStr |
Recent Developments in Metabolomics Studies of Endophytic Fungi |
| title_full_unstemmed |
Recent Developments in Metabolomics Studies of Endophytic Fungi |
| title_sort |
recent developments in metabolomics studies of endophytic fungi |
| publisher |
MDPI |
| publishDate |
2022 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122325825&doi=10.3390%2fjof8010028&partnerID=40&md5=91153a034f90a0d6ccd2bca218f1adfa http://eprints.utp.edu.my/33650/ |
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