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Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring

Mortality level is worsening the situation worldwide thru blood diseases and greatly jeopardizes the human health with poor diagnostics. Due to the lack of successful generation of early diagnosis, the survival rate is currently lower. To overcome the present hurdle, new diagnostic methods have been...

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Main Authors: Letchumanan, I., Gopinath, S.C.B., Md Arshad, M.K., Mohamed Saheed, M.S., Perumal, V., Voon, C.H., Hashim, U.
Format: Article
Published: Taylor and Francis Ltd. 2022
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090443106&doi=10.1080%2f10408347.2020.1812373&partnerID=40&md5=573ebab0f5078b89de49fdb9bc377c63
http://eprints.utp.edu.my/33599/
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spelling my.utp.eprints.335992022-09-07T08:27:33Z Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring Letchumanan, I. Gopinath, S.C.B. Md Arshad, M.K. Mohamed Saheed, M.S. Perumal, V. Voon, C.H. Hashim, U. Mortality level is worsening the situation worldwide thru blood diseases and greatly jeopardizes the human health with poor diagnostics. Due to the lack of successful generation of early diagnosis, the survival rate is currently lower. To overcome the present hurdle, new diagnostic methods have been choreographed for blood disease biomarkers analyses with the conjunction of ultra-small ideal gold nanohybrids. Gold-hybrids hold varieties of unique features, such as high biocompatibility, increased surface-to-volume ratio, less-toxicity, ease in electron transfer and have a greater localized surface plasmon resonance. Gold-nanocomposites can be physically hybrid on the sensor surface and functionalize with the biomolecules using appropriate chemical conjugations. Revolutionizing biosensor platform can be prominently linked for the nanocomposite applications in the current research on medical diagnosis. This review encloses the new developments in diagnosing blood biomarkers by utilizing the gold-nanohybrids. Further, the current state-of-the-art and the future envision with digital monitoring for facile telediagnosis were narrated. © 2020 Taylor & Francis Group, LLC. Taylor and Francis Ltd. 2022 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090443106&doi=10.1080%2f10408347.2020.1812373&partnerID=40&md5=573ebab0f5078b89de49fdb9bc377c63 Letchumanan, I. and Gopinath, S.C.B. and Md Arshad, M.K. and Mohamed Saheed, M.S. and Perumal, V. and Voon, C.H. and Hashim, U. (2022) Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring. Critical Reviews in Analytical Chemistry, 52 (3). pp. 577-592. http://eprints.utp.edu.my/33599/
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Institutional Repository
url_provider http://eprints.utp.edu.my/
description Mortality level is worsening the situation worldwide thru blood diseases and greatly jeopardizes the human health with poor diagnostics. Due to the lack of successful generation of early diagnosis, the survival rate is currently lower. To overcome the present hurdle, new diagnostic methods have been choreographed for blood disease biomarkers analyses with the conjunction of ultra-small ideal gold nanohybrids. Gold-hybrids hold varieties of unique features, such as high biocompatibility, increased surface-to-volume ratio, less-toxicity, ease in electron transfer and have a greater localized surface plasmon resonance. Gold-nanocomposites can be physically hybrid on the sensor surface and functionalize with the biomolecules using appropriate chemical conjugations. Revolutionizing biosensor platform can be prominently linked for the nanocomposite applications in the current research on medical diagnosis. This review encloses the new developments in diagnosing blood biomarkers by utilizing the gold-nanohybrids. Further, the current state-of-the-art and the future envision with digital monitoring for facile telediagnosis were narrated. © 2020 Taylor & Francis Group, LLC.
format Article
author Letchumanan, I.
Gopinath, S.C.B.
Md Arshad, M.K.
Mohamed Saheed, M.S.
Perumal, V.
Voon, C.H.
Hashim, U.
spellingShingle Letchumanan, I.
Gopinath, S.C.B.
Md Arshad, M.K.
Mohamed Saheed, M.S.
Perumal, V.
Voon, C.H.
Hashim, U.
Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
author_facet Letchumanan, I.
Gopinath, S.C.B.
Md Arshad, M.K.
Mohamed Saheed, M.S.
Perumal, V.
Voon, C.H.
Hashim, U.
author_sort Letchumanan, I.
title Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
title_short Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
title_full Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
title_fullStr Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
title_full_unstemmed Gold-Nanohybrid Biosensors for Analyzing Blood Circulating Clinical Biomacromolecules: Current Trend toward Future Remote Digital Monitoring
title_sort gold-nanohybrid biosensors for analyzing blood circulating clinical biomacromolecules: current trend toward future remote digital monitoring
publisher Taylor and Francis Ltd.
publishDate 2022
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090443106&doi=10.1080%2f10408347.2020.1812373&partnerID=40&md5=573ebab0f5078b89de49fdb9bc377c63
http://eprints.utp.edu.my/33599/
_version_ 1744356190715904000
score 13.211869

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