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Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation

The complex physics and biology underlying intracranial hemodynamics are yet to be fully revealed. A fully resolved direct numerical simulation (DNS) study has been performed to identify the intrinsic flow dynamics in an idealized carotid bifurcation model. To shed the light on the significance of c...

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Main Authors: Mahrous, Samar A., Che Sidik, Nor Azwadi, Saqr, Khalid M.
Format: Article
Language:English
Published: Public Library of Science 2021
Subjects:
T Technology (General)
Online Access:http://eprints.utm.my/id/eprint/97878/1/NorAzwadi2021_NumericalStudyOnTheEnergyCascadeOfPulsatile.pdf
http://eprints.utm.my/id/eprint/97878/
http://dx.doi.org/10.1371/journal.pone.0245775
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spelling my.utm.978782022-11-07T10:27:22Z http://eprints.utm.my/id/eprint/97878/ Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation Mahrous, Samar A. Che Sidik, Nor Azwadi Saqr, Khalid M. T Technology (General) The complex physics and biology underlying intracranial hemodynamics are yet to be fully revealed. A fully resolved direct numerical simulation (DNS) study has been performed to identify the intrinsic flow dynamics in an idealized carotid bifurcation model. To shed the light on the significance of considering blood shear-thinning properties, the power-law model is compared to the commonly used Newtonian viscosity hypothesis. We scrutinize the kinetic energy cascade (KEC) rates in the Fourier domain and the vortex structure of both fluid models and examine the impact of the power-law viscosity model. The flow intrinsically contains coherent structures which has frequencies corresponding to the boundary frequency, which could be associated with the regulation of endothelial cells. From the proposed comparative study, it is found that KEC rates and the vortex-identification are significantly influenced by the shear-thinning blood properties. Conclusively, from the obtained results, it is found that neglecting the non-Newtonian behavior could lead to underestimation of the hemodynamic parameters at low Reynolds number and overestimation of the hemodynamic parameters by increasing the Reynolds number. In addition, we provide physical insight and discussion onto the hemodynamics associated with endothelial dysfunction which plays significant role in the pathogenesis of intracranial aneurysms. Copyright: © 2021 Mahrous et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Public Library of Science 2021 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/97878/1/NorAzwadi2021_NumericalStudyOnTheEnergyCascadeOfPulsatile.pdf Mahrous, Samar A. and Che Sidik, Nor Azwadi and Saqr, Khalid M. (2021) Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation. PLoS ONE, 16 (1). pp. 1-19. ISSN 1932-6203 http://dx.doi.org/10.1371/journal.pone.0245775 DOI : 10.1371/journal.pone.0245775
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic T Technology (General)
spellingShingle T Technology (General)
Mahrous, Samar A.
Che Sidik, Nor Azwadi
Saqr, Khalid M.
Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
description The complex physics and biology underlying intracranial hemodynamics are yet to be fully revealed. A fully resolved direct numerical simulation (DNS) study has been performed to identify the intrinsic flow dynamics in an idealized carotid bifurcation model. To shed the light on the significance of considering blood shear-thinning properties, the power-law model is compared to the commonly used Newtonian viscosity hypothesis. We scrutinize the kinetic energy cascade (KEC) rates in the Fourier domain and the vortex structure of both fluid models and examine the impact of the power-law viscosity model. The flow intrinsically contains coherent structures which has frequencies corresponding to the boundary frequency, which could be associated with the regulation of endothelial cells. From the proposed comparative study, it is found that KEC rates and the vortex-identification are significantly influenced by the shear-thinning blood properties. Conclusively, from the obtained results, it is found that neglecting the non-Newtonian behavior could lead to underestimation of the hemodynamic parameters at low Reynolds number and overestimation of the hemodynamic parameters by increasing the Reynolds number. In addition, we provide physical insight and discussion onto the hemodynamics associated with endothelial dysfunction which plays significant role in the pathogenesis of intracranial aneurysms. Copyright: © 2021 Mahrous et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
format Article
author Mahrous, Samar A.
Che Sidik, Nor Azwadi
Saqr, Khalid M.
author_facet Mahrous, Samar A.
Che Sidik, Nor Azwadi
Saqr, Khalid M.
author_sort Mahrous, Samar A.
title Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
title_short Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
title_full Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
title_fullStr Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
title_full_unstemmed Numerical study on the energy cascade of pulsatile Newtonian and power-law flow models in an ICA bifurcation
title_sort numerical study on the energy cascade of pulsatile newtonian and power-law flow models in an ica bifurcation
publisher Public Library of Science
publishDate 2021
url http://eprints.utm.my/id/eprint/97878/1/NorAzwadi2021_NumericalStudyOnTheEnergyCascadeOfPulsatile.pdf
http://eprints.utm.my/id/eprint/97878/
http://dx.doi.org/10.1371/journal.pone.0245775
_version_ 1751536116261978112
score 13.222552

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