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Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints

Iron (Fe) and Fe-based scaffolds have become a research frontier in absorbable materials which is inherent to their promising mechanical properties including fatigue strength and ductility. Nevertheless, their slow corrosion rate and low biocompatibility have been their major obstacles to be applied...

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Main Authors: Md. Yusop, Abdul Hakim, Al Sakkaf, Ahmed, Nur, Hadi
Format: Article
Published: John Wiley and Sons Inc 2022
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/97693/
http://dx.doi.org/10.1002/jbm.b.34893
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spelling my.utm.976932022-10-31T01:06:29Z http://eprints.utm.my/id/eprint/97693/ Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints Md. Yusop, Abdul Hakim Al Sakkaf, Ahmed Nur, Hadi QD Chemistry Iron (Fe) and Fe-based scaffolds have become a research frontier in absorbable materials which is inherent to their promising mechanical properties including fatigue strength and ductility. Nevertheless, their slow corrosion rate and low biocompatibility have been their major obstacles to be applied in clinical applications. Over the last decade, various modifications on porous Fe-based scaffolds have been performed to ameliorate both properties encompassing surface coating, microstructural alteration via alloying, and advanced topologically order structural design produced by additive manufacturing (AM) techniques. The recent advent of AM produces topologically ordered porous Fe-based structures with an optimized architecture having controllable pore size and strut thickness, intricate internal design, and larger exposed surface area. This undoubtedly opens up new options for controlling Fe corrosion and its structural strengths. However, the in vitro biocompatibility of the AM porous Fe still needs to be addressed considering its higher corrosion rate due to the larger exposed surface area. This review summarizes the latest progress of the modifications on porous Fe-based scaffolds with a specific focus on their responses on the corrosion behavior and biocompatibility. John Wiley and Sons Inc 2022 Article PeerReviewed Md. Yusop, Abdul Hakim and Al Sakkaf, Ahmed and Nur, Hadi (2022) Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 110 (1). pp. 18-44. ISSN 1552-4973 http://dx.doi.org/10.1002/jbm.b.34893 DOI : 10.1002/jbm.b.34893
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Md. Yusop, Abdul Hakim
Al Sakkaf, Ahmed
Nur, Hadi
Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
description Iron (Fe) and Fe-based scaffolds have become a research frontier in absorbable materials which is inherent to their promising mechanical properties including fatigue strength and ductility. Nevertheless, their slow corrosion rate and low biocompatibility have been their major obstacles to be applied in clinical applications. Over the last decade, various modifications on porous Fe-based scaffolds have been performed to ameliorate both properties encompassing surface coating, microstructural alteration via alloying, and advanced topologically order structural design produced by additive manufacturing (AM) techniques. The recent advent of AM produces topologically ordered porous Fe-based structures with an optimized architecture having controllable pore size and strut thickness, intricate internal design, and larger exposed surface area. This undoubtedly opens up new options for controlling Fe corrosion and its structural strengths. However, the in vitro biocompatibility of the AM porous Fe still needs to be addressed considering its higher corrosion rate due to the larger exposed surface area. This review summarizes the latest progress of the modifications on porous Fe-based scaffolds with a specific focus on their responses on the corrosion behavior and biocompatibility.
format Article
author Md. Yusop, Abdul Hakim
Al Sakkaf, Ahmed
Nur, Hadi
author_facet Md. Yusop, Abdul Hakim
Al Sakkaf, Ahmed
Nur, Hadi
author_sort Md. Yusop, Abdul Hakim
title Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
title_short Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
title_full Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
title_fullStr Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
title_full_unstemmed Modifications on porous absorbable Fe-based scaffolds for bone applications: A review from corrosion and biocompatibility viewpoints
title_sort modifications on porous absorbable fe-based scaffolds for bone applications: a review from corrosion and biocompatibility viewpoints
publisher John Wiley and Sons Inc
publishDate 2022
url http://eprints.utm.my/id/eprint/97693/
http://dx.doi.org/10.1002/jbm.b.34893
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score 13.211869

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