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Recent update on the anti-infective potential of carboline analogs

β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacte-rial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and anti-thrombot...

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Main Authors: Faheem, F., Kumar, B. K., Sekhar, K. V. G. C., Kun-Jiappan, S., Jamalis, J., Rafael, B. F., Sankaranarayanan, M.
Format: Article
Published: Bentham Science Publishers 2021
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/96513/
http://dx.doi.org/10.2174/1389557520666201001130114
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spelling my.utm.965132022-07-26T08:01:47Z http://eprints.utm.my/id/eprint/96513/ Recent update on the anti-infective potential of carboline analogs Faheem, F. Kumar, B. K. Sekhar, K. V. G. C. Kun-Jiappan, S. Jamalis, J. Rafael, B. F. Sankaranarayanan, M. QD Chemistry β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacte-rial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and anti-thrombotic among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms. This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishma-nial and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism of action is also added. Bentham Science Publishers 2021 Article PeerReviewed Faheem, F. and Kumar, B. K. and Sekhar, K. V. G. C. and Kun-Jiappan, S. and Jamalis, J. and Rafael, B. F. and Sankaranarayanan, M. (2021) Recent update on the anti-infective potential of carboline analogs. Mini-Reviews in Medicinal Chemistry, 21 (4). pp. 398-425. ISSN 1389-5575 http://dx.doi.org/10.2174/1389557520666201001130114 DOI: 10.2174/1389557520666201001130114
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Faheem, F.
Kumar, B. K.
Sekhar, K. V. G. C.
Kun-Jiappan, S.
Jamalis, J.
Rafael, B. F.
Sankaranarayanan, M.
Recent update on the anti-infective potential of carboline analogs
description β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacte-rial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and anti-thrombotic among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms. This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishma-nial and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism of action is also added.
format Article
author Faheem, F.
Kumar, B. K.
Sekhar, K. V. G. C.
Kun-Jiappan, S.
Jamalis, J.
Rafael, B. F.
Sankaranarayanan, M.
author_facet Faheem, F.
Kumar, B. K.
Sekhar, K. V. G. C.
Kun-Jiappan, S.
Jamalis, J.
Rafael, B. F.
Sankaranarayanan, M.
author_sort Faheem, F.
title Recent update on the anti-infective potential of carboline analogs
title_short Recent update on the anti-infective potential of carboline analogs
title_full Recent update on the anti-infective potential of carboline analogs
title_fullStr Recent update on the anti-infective potential of carboline analogs
title_full_unstemmed Recent update on the anti-infective potential of carboline analogs
title_sort recent update on the anti-infective potential of carboline analogs
publisher Bentham Science Publishers
publishDate 2021
url http://eprints.utm.my/id/eprint/96513/
http://dx.doi.org/10.2174/1389557520666201001130114
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score 13.211869

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