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Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement

A new potential biomimetic polymeric 3D scaffold is fabricated using collagen entrapment and 3D printed polylactic acid scaffold. The modified scaffold was characterized by compressive modulus, degree of swelling, water contact angle (WCA), and Fourier Transform Infrared Spectroscopy (FTIR). The fin...

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Main Authors: Hamzah, M. S. A., Ng., C., Zulkarnain, N. I. S., Majid, H. A., Ab. Razak, S. I., Mat Nayan, N. H.
Format: Conference or Workshop Item
Language:English
Published: 2021
Subjects:
TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/95837/1/SaifulIzwanAbdRazak2021_EntrapmentofCollagenonPolylactic.pdf
http://eprints.utm.my/id/eprint/95837/
http://dx.doi.org/10.1016/j.matpr.2020.07.263
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spelling my.utm.958372022-06-19T08:09:38Z http://eprints.utm.my/id/eprint/95837/ Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement Hamzah, M. S. A. Ng., C. Zulkarnain, N. I. S. Majid, H. A. Ab. Razak, S. I. Mat Nayan, N. H. TP Chemical technology A new potential biomimetic polymeric 3D scaffold is fabricated using collagen entrapment and 3D printed polylactic acid scaffold. The modified scaffold was characterized by compressive modulus, degree of swelling, water contact angle (WCA), and Fourier Transform Infrared Spectroscopy (FTIR). The findings show that sample PLA/col40 with 40s entrapment duration is the optimum composition that meets the requirement for artificial bone tissue replacement. In vitro biomineralization using simulated body fluid (SBF) demonstrates that the PLA/collagen 3D scaffold is able to promote the growth of hydroxyapatite (HA) after 7days which will subsequently improve the osteoconductive and osteoinductive properties of the 3D scaffold. The overall results suggest the potential of the 3D PLA/collagen scaffold as a prospective material for bone tissue engineering applications. 2021 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/95837/1/SaifulIzwanAbdRazak2021_EntrapmentofCollagenonPolylactic.pdf Hamzah, M. S. A. and Ng., C. and Zulkarnain, N. I. S. and Majid, H. A. and Ab. Razak, S. I. and Mat Nayan, N. H. (2021) Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement. In: Innovative Manufacturing, Mechatronics and Materials Forum, iM3F 2020, 6 August 2020, Pekan, Pahang. http://dx.doi.org/10.1016/j.matpr.2020.07.263
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Hamzah, M. S. A.
Ng., C.
Zulkarnain, N. I. S.
Majid, H. A.
Ab. Razak, S. I.
Mat Nayan, N. H.
Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
description A new potential biomimetic polymeric 3D scaffold is fabricated using collagen entrapment and 3D printed polylactic acid scaffold. The modified scaffold was characterized by compressive modulus, degree of swelling, water contact angle (WCA), and Fourier Transform Infrared Spectroscopy (FTIR). The findings show that sample PLA/col40 with 40s entrapment duration is the optimum composition that meets the requirement for artificial bone tissue replacement. In vitro biomineralization using simulated body fluid (SBF) demonstrates that the PLA/collagen 3D scaffold is able to promote the growth of hydroxyapatite (HA) after 7days which will subsequently improve the osteoconductive and osteoinductive properties of the 3D scaffold. The overall results suggest the potential of the 3D PLA/collagen scaffold as a prospective material for bone tissue engineering applications.
format Conference or Workshop Item
author Hamzah, M. S. A.
Ng., C.
Zulkarnain, N. I. S.
Majid, H. A.
Ab. Razak, S. I.
Mat Nayan, N. H.
author_facet Hamzah, M. S. A.
Ng., C.
Zulkarnain, N. I. S.
Majid, H. A.
Ab. Razak, S. I.
Mat Nayan, N. H.
author_sort Hamzah, M. S. A.
title Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
title_short Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
title_full Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
title_fullStr Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
title_full_unstemmed Entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
title_sort entrapment of collagen on polylactic acid 3d scaffold surface as a potential artificial bone replacement
publishDate 2021
url http://eprints.utm.my/id/eprint/95837/1/SaifulIzwanAbdRazak2021_EntrapmentofCollagenonPolylactic.pdf
http://eprints.utm.my/id/eprint/95837/
http://dx.doi.org/10.1016/j.matpr.2020.07.263
_version_ 1736833513676603392
score 13.211869

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