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Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection

Conventional biopsy, based on extraction from a tumor of a solid tissue specimen requiring needles, endoscopic devices, excision or surgery, is at risk of infection, internal bleeding or prolonged recovery. A non-invasive liquid biopsy is one of the greatest axiomatic consequences of the identificat...

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Main Authors: Balakrishnan, S. G., Ahmad, M. R., Koloor, S. S. R.
Format: Article
Language:English
Published: Elsevier B.V. 2021
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://eprints.utm.my/id/eprint/94974/1/MohdRidzuanAhmad2021_SeparationofctDNAbySuperparamagnetic.pdf
http://eprints.utm.my/id/eprint/94974/
http://dx.doi.org/10.1016/j.jare.2021.03.001
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id my.utm.94974
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spelling my.utm.949742022-04-29T22:00:14Z http://eprints.utm.my/id/eprint/94974/ Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection Balakrishnan, S. G. Ahmad, M. R. Koloor, S. S. R. TK Electrical engineering. Electronics Nuclear engineering Conventional biopsy, based on extraction from a tumor of a solid tissue specimen requiring needles, endoscopic devices, excision or surgery, is at risk of infection, internal bleeding or prolonged recovery. A non-invasive liquid biopsy is one of the greatest axiomatic consequences of the identification of circulating tumor DNA (ctDNA) as a replaceable surgical tumor bioQpsy technique. Most of the literature studies thus far presented ctDNA detection at almost final stage III or IV of cancer, where the treatment option or cancer management is nearly impossible for diagnosis. Elsevier B.V. 2021 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/94974/1/MohdRidzuanAhmad2021_SeparationofctDNAbySuperparamagnetic.pdf Balakrishnan, S. G. and Ahmad, M. R. and Koloor, S. S. R. (2021) Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection. Journal of Advanced Research, 33 . ISSN 2090-1232 http://dx.doi.org/10.1016/j.jare.2021.03.001 DOI: 10.1016/j.jare.2021.03.001
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Balakrishnan, S. G.
Ahmad, M. R.
Koloor, S. S. R.
Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
description Conventional biopsy, based on extraction from a tumor of a solid tissue specimen requiring needles, endoscopic devices, excision or surgery, is at risk of infection, internal bleeding or prolonged recovery. A non-invasive liquid biopsy is one of the greatest axiomatic consequences of the identification of circulating tumor DNA (ctDNA) as a replaceable surgical tumor bioQpsy technique. Most of the literature studies thus far presented ctDNA detection at almost final stage III or IV of cancer, where the treatment option or cancer management is nearly impossible for diagnosis.
format Article
author Balakrishnan, S. G.
Ahmad, M. R.
Koloor, S. S. R.
author_facet Balakrishnan, S. G.
Ahmad, M. R.
Koloor, S. S. R.
author_sort Balakrishnan, S. G.
title Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
title_short Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
title_full Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
title_fullStr Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
title_full_unstemmed Separation of ctDNA by superparamagnetic bead particles in microfluidic platform for early cancer detection
title_sort separation of ctdna by superparamagnetic bead particles in microfluidic platform for early cancer detection
publisher Elsevier B.V.
publishDate 2021
url http://eprints.utm.my/id/eprint/94974/1/MohdRidzuanAhmad2021_SeparationofctDNAbySuperparamagnetic.pdf
http://eprints.utm.my/id/eprint/94974/
http://dx.doi.org/10.1016/j.jare.2021.03.001
_version_ 1732945416790474752
score 13.211869

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