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Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications

Iron (Fe) and Fe-based materials have been vigorously explored in orthopedic applications in the past decade mainly owing to their promising mechanical properties including high yield strength, elastic modulus and ductility. Nevertheless, their corrosion products and low corrosion kinetics are the m...

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Main Authors: Md. Yusop, Abdul Hakim, Ulum, Mokhamad Fakhrul, Al Sakkaf, Ahmed, Hartanto, Djoko, Nur, Hadi
Format: Article
Published: John Wiley and Sons Inc 2021
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://eprints.utm.my/id/eprint/94484/
http://dx.doi.org/10.1002/biot.202100255
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spelling my.utm.944842022-03-31T15:46:26Z http://eprints.utm.my/id/eprint/94484/ Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications Md. Yusop, Abdul Hakim Ulum, Mokhamad Fakhrul Al Sakkaf, Ahmed Hartanto, Djoko Nur, Hadi TJ Mechanical engineering and machinery Iron (Fe) and Fe-based materials have been vigorously explored in orthopedic applications in the past decade mainly owing to their promising mechanical properties including high yield strength, elastic modulus and ductility. Nevertheless, their corrosion products and low corrosion kinetics are the major concerns that need to be improved further despite their appealing mechanical strengths. The current studies on porous Fe-based scaffolds show an improved corrosion rate but the in vitro biocompatibility is still problematic in general. Unlike the Mg implants, the biodegradation and bioabsorption of Fe-based implants are still not well described. This vague issue could implicate the development of Fe-based materials as potential medical implants as they have not reached the clinical trial stage yet. Thus, there is a need to understand in-depth the Fe corrosion behavior and its bioabsorption mechanism to facilitate the material design of Fe-based scaffolds and further improve its biocompatibility. This manuscript provides an important insight into the basic bioabsorption of the multi-ranged Fe-based corrosion products with a review of the latest progress on the corrosion & in vitro biocompatibility of porous Fe-based scaffolds together with the remaining challenges and the perspective on the future direction. John Wiley and Sons Inc 2021-12 Article PeerReviewed Md. Yusop, Abdul Hakim and Ulum, Mokhamad Fakhrul and Al Sakkaf, Ahmed and Hartanto, Djoko and Nur, Hadi (2021) Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications. Biotechnology Journal, 16 (12). ISSN 1860-6768 http://dx.doi.org/10.1002/biot.202100255 DOI:10.1002/biot.202100255
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Md. Yusop, Abdul Hakim
Ulum, Mokhamad Fakhrul
Al Sakkaf, Ahmed
Hartanto, Djoko
Nur, Hadi
Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
description Iron (Fe) and Fe-based materials have been vigorously explored in orthopedic applications in the past decade mainly owing to their promising mechanical properties including high yield strength, elastic modulus and ductility. Nevertheless, their corrosion products and low corrosion kinetics are the major concerns that need to be improved further despite their appealing mechanical strengths. The current studies on porous Fe-based scaffolds show an improved corrosion rate but the in vitro biocompatibility is still problematic in general. Unlike the Mg implants, the biodegradation and bioabsorption of Fe-based implants are still not well described. This vague issue could implicate the development of Fe-based materials as potential medical implants as they have not reached the clinical trial stage yet. Thus, there is a need to understand in-depth the Fe corrosion behavior and its bioabsorption mechanism to facilitate the material design of Fe-based scaffolds and further improve its biocompatibility. This manuscript provides an important insight into the basic bioabsorption of the multi-ranged Fe-based corrosion products with a review of the latest progress on the corrosion & in vitro biocompatibility of porous Fe-based scaffolds together with the remaining challenges and the perspective on the future direction.
format Article
author Md. Yusop, Abdul Hakim
Ulum, Mokhamad Fakhrul
Al Sakkaf, Ahmed
Hartanto, Djoko
Nur, Hadi
author_facet Md. Yusop, Abdul Hakim
Ulum, Mokhamad Fakhrul
Al Sakkaf, Ahmed
Hartanto, Djoko
Nur, Hadi
author_sort Md. Yusop, Abdul Hakim
title Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
title_short Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
title_full Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
title_fullStr Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
title_full_unstemmed Insight into the bioabsorption of Fe‐based materials & their current developments in bone applications
title_sort insight into the bioabsorption of fe‐based materials & their current developments in bone applications
publisher John Wiley and Sons Inc
publishDate 2021
url http://eprints.utm.my/id/eprint/94484/
http://dx.doi.org/10.1002/biot.202100255
_version_ 1729703178690101248
score 13.211869

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