Staff View: Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation

Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation

A new strategy to recycle dialysate within a system is needed to foster the progress of developing wearable artificial kidney as an alternative to conventional hemodialysis practices. This study presents an attractive approach to collectively remove uremic toxins by combining membrane filtration and...

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Main Authors:	Zainol Abidin, Muhammad Nidzhom, Goh, Pei Sean, Said, Noresah, Ismail, Ahmad Fauzi, Othman, Mohd. Hafiz Dzarfan, Abdullah, Mohd. Sohaimi, Ng, Be Cheer, Hasbullah, Hasrinah, Sheikh Abdul Kadir, Siti Hamimah, Kamal, Fatmawati, Mansur, Sumarni
Format:	Article
Published:	Elsevier B.V. 2020
Subjects:	TP Chemical technology
Online Access:	http://eprints.utm.my/id/eprint/90871/ http://dx.doi.org/10.1016/j.seppur.2019.116216
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id	my.utm.90871
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spelling	my.utm.908712021-05-31T13:40:06Z http://eprints.utm.my/id/eprint/90871/ Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation Zainol Abidin, Muhammad Nidzhom Goh, Pei Sean Said, Noresah Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Abdullah, Mohd. Sohaimi Ng, Be Cheer Hasbullah, Hasrinah Sheikh Abdul Kadir, Siti Hamimah Kamal, Fatmawati Mansur, Sumarni TP Chemical technology A new strategy to recycle dialysate within a system is needed to foster the progress of developing wearable artificial kidney as an alternative to conventional hemodialysis practices. This study presents an attractive approach to collectively remove uremic toxins by combining membrane filtration and adsorption process. In this work, dual layer hollow fiber (DLHF) membranes consisting of polysulfone (PSf) inner layer well attached to PSf/amino-silanized poly(methyl methacrylate (N-PMMA) outer layer were prepared via co-extrusion spinning process based on non-solvent induced phase separation. The PSf/N-PMMA DLHF membranes were characterized and evaluated in terms of urea adsorption capacity and filtration performance. It was revealed that the urea adsorption onto N-PMMA is a non-spontaneous physical process that follows Freundlich isotherm model and pseudo-second-order kinetic model. Results showed that the membrane exhibited urea adsorption capacity of up to 27.6 mg/g depending on N-PMMA content. Under dynamic filtration condition, the membranes demonstrated significant urea removal (39.2%) and showed desired sieving characteristics for other solutes. The design of DLHF membrane with adsorptive property is an exciting prospect that would become a key solution for dialysate regeneration. Elsevier B.V. 2020-04 Article PeerReviewed Zainol Abidin, Muhammad Nidzhom and Goh, Pei Sean and Said, Noresah and Ismail, Ahmad Fauzi and Othman, Mohd. Hafiz Dzarfan and Abdullah, Mohd. Sohaimi and Ng, Be Cheer and Hasbullah, Hasrinah and Sheikh Abdul Kadir, Siti Hamimah and Kamal, Fatmawati and Mansur, Sumarni (2020) Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation. Separation and Purification Technology, 236 . ISSN 1383-5866 http://dx.doi.org/10.1016/j.seppur.2019.116216 DOI:10.1016/j.seppur.2019.116216
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
topic	TP Chemical technology
spellingShingle	TP Chemical technology Zainol Abidin, Muhammad Nidzhom Goh, Pei Sean Said, Noresah Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Abdullah, Mohd. Sohaimi Ng, Be Cheer Hasbullah, Hasrinah Sheikh Abdul Kadir, Siti Hamimah Kamal, Fatmawati Mansur, Sumarni Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
description	A new strategy to recycle dialysate within a system is needed to foster the progress of developing wearable artificial kidney as an alternative to conventional hemodialysis practices. This study presents an attractive approach to collectively remove uremic toxins by combining membrane filtration and adsorption process. In this work, dual layer hollow fiber (DLHF) membranes consisting of polysulfone (PSf) inner layer well attached to PSf/amino-silanized poly(methyl methacrylate (N-PMMA) outer layer were prepared via co-extrusion spinning process based on non-solvent induced phase separation. The PSf/N-PMMA DLHF membranes were characterized and evaluated in terms of urea adsorption capacity and filtration performance. It was revealed that the urea adsorption onto N-PMMA is a non-spontaneous physical process that follows Freundlich isotherm model and pseudo-second-order kinetic model. Results showed that the membrane exhibited urea adsorption capacity of up to 27.6 mg/g depending on N-PMMA content. Under dynamic filtration condition, the membranes demonstrated significant urea removal (39.2%) and showed desired sieving characteristics for other solutes. The design of DLHF membrane with adsorptive property is an exciting prospect that would become a key solution for dialysate regeneration.
format	Article
author	Zainol Abidin, Muhammad Nidzhom Goh, Pei Sean Said, Noresah Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Abdullah, Mohd. Sohaimi Ng, Be Cheer Hasbullah, Hasrinah Sheikh Abdul Kadir, Siti Hamimah Kamal, Fatmawati Mansur, Sumarni
author_facet	Zainol Abidin, Muhammad Nidzhom Goh, Pei Sean Said, Noresah Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Abdullah, Mohd. Sohaimi Ng, Be Cheer Hasbullah, Hasrinah Sheikh Abdul Kadir, Siti Hamimah Kamal, Fatmawati Mansur, Sumarni
author_sort	Zainol Abidin, Muhammad Nidzhom
title	Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
title_short	Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
title_full	Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
title_fullStr	Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
title_full_unstemmed	Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
title_sort	polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation
publisher	Elsevier B.V.
publishDate	2020
url	http://eprints.utm.my/id/eprint/90871/ http://dx.doi.org/10.1016/j.seppur.2019.116216
_version_	1702169613573292032
score	13.211869

Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation

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