Review on nanocrystalline cellulose in bone tissue engineering applications
Nanocrystalline cellulose is an abundant and inexhaustible organic material on Earth. It can be derived from many lignocellulosic plants and also from agricultural residues. They endowed exceptional physicochemical properties, which have promoted their intensive exploration in biomedical application...
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Online Access: | http://eprints.utm.my/id/eprint/90226/1/NorHasrulAkhmal2020_ReviewonNanocrystallineCelluloseinBoneTissue.pdf http://eprints.utm.my/id/eprint/90226/ http://dx.doi.org/10.3390/polym12122818 |
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my.utm.902262021-03-31T06:22:51Z http://eprints.utm.my/id/eprint/90226/ Review on nanocrystalline cellulose in bone tissue engineering applications Murizan, Nur Ilyana Sahira Mustafa, Nur Syahirah Ngadiman, Nor Hasrul Akhmal Mohd. Yusof, Noordin Idris, Ani TJ Mechanical engineering and machinery Nanocrystalline cellulose is an abundant and inexhaustible organic material on Earth. It can be derived from many lignocellulosic plants and also from agricultural residues. They endowed exceptional physicochemical properties, which have promoted their intensive exploration in biomedical application, especially for tissue engineering scaffolds. Nanocrystalline cellulose has been acknowledged due to its low toxicity and low ecotoxicological risks towards living cells. To explore this field, this review provides an overview of nanocrystalline cellulose in designing materials of bone scaffolds. An introduction to nanocrystalline cellulose and its isolation method of acid hydrolysis are discussed following by the application of nanocrystalline cellulose in bone tissue engineering scaffolds. This review also provides comprehensive knowledge and highlights the contribution of nanocrystalline cellulose in terms of mechanical properties, biocompatibility and biodegradability of bone tissue engineering scaffolds. Lastly, the challenges for future scaffold development using nanocrystalline cellulose are also included. MDPI AG 2020-12 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/90226/1/NorHasrulAkhmal2020_ReviewonNanocrystallineCelluloseinBoneTissue.pdf Murizan, Nur Ilyana Sahira and Mustafa, Nur Syahirah and Ngadiman, Nor Hasrul Akhmal and Mohd. Yusof, Noordin and Idris, Ani (2020) Review on nanocrystalline cellulose in bone tissue engineering applications. Polymers, 12 (12). pp. 1-22. ISSN 2073-4360 http://dx.doi.org/10.3390/polym12122818 |
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TJ Mechanical engineering and machinery Murizan, Nur Ilyana Sahira Mustafa, Nur Syahirah Ngadiman, Nor Hasrul Akhmal Mohd. Yusof, Noordin Idris, Ani Review on nanocrystalline cellulose in bone tissue engineering applications |
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Nanocrystalline cellulose is an abundant and inexhaustible organic material on Earth. It can be derived from many lignocellulosic plants and also from agricultural residues. They endowed exceptional physicochemical properties, which have promoted their intensive exploration in biomedical application, especially for tissue engineering scaffolds. Nanocrystalline cellulose has been acknowledged due to its low toxicity and low ecotoxicological risks towards living cells. To explore this field, this review provides an overview of nanocrystalline cellulose in designing materials of bone scaffolds. An introduction to nanocrystalline cellulose and its isolation method of acid hydrolysis are discussed following by the application of nanocrystalline cellulose in bone tissue engineering scaffolds. This review also provides comprehensive knowledge and highlights the contribution of nanocrystalline cellulose in terms of mechanical properties, biocompatibility and biodegradability of bone tissue engineering scaffolds. Lastly, the challenges for future scaffold development using nanocrystalline cellulose are also included. |
format |
Article |
author |
Murizan, Nur Ilyana Sahira Mustafa, Nur Syahirah Ngadiman, Nor Hasrul Akhmal Mohd. Yusof, Noordin Idris, Ani |
author_facet |
Murizan, Nur Ilyana Sahira Mustafa, Nur Syahirah Ngadiman, Nor Hasrul Akhmal Mohd. Yusof, Noordin Idris, Ani |
author_sort |
Murizan, Nur Ilyana Sahira |
title |
Review on nanocrystalline cellulose in bone tissue engineering applications |
title_short |
Review on nanocrystalline cellulose in bone tissue engineering applications |
title_full |
Review on nanocrystalline cellulose in bone tissue engineering applications |
title_fullStr |
Review on nanocrystalline cellulose in bone tissue engineering applications |
title_full_unstemmed |
Review on nanocrystalline cellulose in bone tissue engineering applications |
title_sort |
review on nanocrystalline cellulose in bone tissue engineering applications |
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MDPI AG |
publishDate |
2020 |
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http://eprints.utm.my/id/eprint/90226/1/NorHasrulAkhmal2020_ReviewonNanocrystallineCelluloseinBoneTissue.pdf http://eprints.utm.my/id/eprint/90226/ http://dx.doi.org/10.3390/polym12122818 |
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