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Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment

Descemet membrane detachment (DMD) is a tear or break on the Descement membrane (DM) which is a part of the cornea membrane. DMD is occurred when DM separate from stroma. The separation is due to the aqueous humour (AH) flows into the subspaces between the stroma and DM. A mathematical model of buoy...

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Main Authors: Woon, Woan Jen, Ismail, Zuhaila, Fitt, Alistair
Format: Article
Language:English
Published: Penerbit Akademia Baru 2020
Subjects:
QA Mathematics
Online Access:http://eprints.utm.my/id/eprint/90079/1/ZuhailaIsmail2020_SimulationofAqueousHumourFlowDrivenbyBuoyancyEffects.pdf
http://eprints.utm.my/id/eprint/90079/
http://dx.doi.org/10.37934/cfdl.12.4.1223
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spelling my.utm.900792021-03-31T05:04:28Z http://eprints.utm.my/id/eprint/90079/ Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment Woon, Woan Jen Ismail, Zuhaila Fitt, Alistair QA Mathematics Descemet membrane detachment (DMD) is a tear or break on the Descement membrane (DM) which is a part of the cornea membrane. DMD is occurred when DM separate from stroma. The separation is due to the aqueous humour (AH) flows into the subspaces between the stroma and DM. A mathematical model of buoyancy driven AH flow is developed to analyse the behaviour of the fluid flows through the pupil aperture in anterior chamber (AC) during DMD. Finite element method using COMSOL Multiphysics 5.2 is implemented to simulate the buoyancy driven flow of AH enters the AC across pupil aperture and leaves through Trabecular meshwork (TM) during DMD. Results are obtained for the eye in standing and supine position. The effects considered is the temperature differences between the cornea and iris that act as the driver of AH flow, variation of pupil size indicate the different level of ambient light and the influence of gravity on the deformation of DMD. Buoyancy effect is observed to be the dominant driven mechanism of AH flow in AC. Variation of pupil size has no effect on the pattern of the fluid flow in AC. The standing and supine position of human are able to change the recirculation pattern of AH in the AC. Therefore, the reattachment of DMD is significantly affected by the body position of the patient. Penerbit Akademia Baru 2020 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/90079/1/ZuhailaIsmail2020_SimulationofAqueousHumourFlowDrivenbyBuoyancyEffects.pdf Woon, Woan Jen and Ismail, Zuhaila and Fitt, Alistair (2020) Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment. CFD Letters, 12 (4). pp. 12-23. ISSN 2180-1363 http://dx.doi.org/10.37934/cfdl.12.4.1223
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic QA Mathematics
spellingShingle QA Mathematics
Woon, Woan Jen
Ismail, Zuhaila
Fitt, Alistair
Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
description Descemet membrane detachment (DMD) is a tear or break on the Descement membrane (DM) which is a part of the cornea membrane. DMD is occurred when DM separate from stroma. The separation is due to the aqueous humour (AH) flows into the subspaces between the stroma and DM. A mathematical model of buoyancy driven AH flow is developed to analyse the behaviour of the fluid flows through the pupil aperture in anterior chamber (AC) during DMD. Finite element method using COMSOL Multiphysics 5.2 is implemented to simulate the buoyancy driven flow of AH enters the AC across pupil aperture and leaves through Trabecular meshwork (TM) during DMD. Results are obtained for the eye in standing and supine position. The effects considered is the temperature differences between the cornea and iris that act as the driver of AH flow, variation of pupil size indicate the different level of ambient light and the influence of gravity on the deformation of DMD. Buoyancy effect is observed to be the dominant driven mechanism of AH flow in AC. Variation of pupil size has no effect on the pattern of the fluid flow in AC. The standing and supine position of human are able to change the recirculation pattern of AH in the AC. Therefore, the reattachment of DMD is significantly affected by the body position of the patient.
format Article
author Woon, Woan Jen
Ismail, Zuhaila
Fitt, Alistair
author_facet Woon, Woan Jen
Ismail, Zuhaila
Fitt, Alistair
author_sort Woon, Woan Jen
title Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
title_short Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
title_full Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
title_fullStr Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
title_full_unstemmed Simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
title_sort simulation of aqueous humour flow driven by buoyancy effects and flow through pupil aperture during descemet membrane detachment
publisher Penerbit Akademia Baru
publishDate 2020
url http://eprints.utm.my/id/eprint/90079/1/ZuhailaIsmail2020_SimulationofAqueousHumourFlowDrivenbyBuoyancyEffects.pdf
http://eprints.utm.my/id/eprint/90079/
http://dx.doi.org/10.37934/cfdl.12.4.1223
_version_ 1696976258324234240
score 13.211869

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