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Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia

Truffles are consumed worldwide as a type of precious food. Desert truffles are characterized by their growth under extreme soil and climate conditions. They have numerous nutritional and medicinal applications. Desert truffles have been shown to exhibit various biological activities. During the pre...

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Main Authors: Elsayed, Elsayed Ahmed, Alsahli, F. D., Barakat, Ibrahim Abdalla Hassan, El Enshasy, Hesham A., Wadaan, M. A.
Format: Article
Language:English
Published: Scientific Publishers 2019
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/87684/1/HeshamAElEnshasy2019_AssessmentofInVitroAntimicrobialandAntiBreast.pdf
http://eprints.utm.my/id/eprint/87684/
http://nopr.niscair.res.in/handle/123456789/48789
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spelling my.utm.876842020-11-30T13:08:39Z http://eprints.utm.my/id/eprint/87684/ Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia Elsayed, Elsayed Ahmed Alsahli, F. D. Barakat, Ibrahim Abdalla Hassan El Enshasy, Hesham A. Wadaan, M. A. QD Chemistry Truffles are consumed worldwide as a type of precious food. Desert truffles are characterized by their growth under extreme soil and climate conditions. They have numerous nutritional and medicinal applications. Desert truffles have been shown to exhibit various biological activities. During the present work, we identified two truffle types collected from Riyadh Province, Kingdom of Saudi Arabia, as Tirmania nivea and Terfezia claveryi. Their extracts showed significant antimicrobial activity against Bacillus subtilis, while the activity was less obvious against Escherichia coli. Hexane and ethyl acetate extracts of both types showed a dose-dependent effect against MCF-7 cancer cells, where their highest toxicities ranged from 91-93%. The lowest effective IC 50 values were 378.9±0.96 and 215.8±0.92 μg/mL for T. nivea and T. claveryi, respectively. Scientific Publishers 2019-07 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/87684/1/HeshamAElEnshasy2019_AssessmentofInVitroAntimicrobialandAntiBreast.pdf Elsayed, Elsayed Ahmed and Alsahli, F. D. and Barakat, Ibrahim Abdalla Hassan and El Enshasy, Hesham A. and Wadaan, M. A. (2019) Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia. Journal of Scientific and Industrial Research, 78 (7). pp. 419-425. ISSN 0022-4456 http://nopr.niscair.res.in/handle/123456789/48789
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Elsayed, Elsayed Ahmed
Alsahli, F. D.
Barakat, Ibrahim Abdalla Hassan
El Enshasy, Hesham A.
Wadaan, M. A.
Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
description Truffles are consumed worldwide as a type of precious food. Desert truffles are characterized by their growth under extreme soil and climate conditions. They have numerous nutritional and medicinal applications. Desert truffles have been shown to exhibit various biological activities. During the present work, we identified two truffle types collected from Riyadh Province, Kingdom of Saudi Arabia, as Tirmania nivea and Terfezia claveryi. Their extracts showed significant antimicrobial activity against Bacillus subtilis, while the activity was less obvious against Escherichia coli. Hexane and ethyl acetate extracts of both types showed a dose-dependent effect against MCF-7 cancer cells, where their highest toxicities ranged from 91-93%. The lowest effective IC 50 values were 378.9±0.96 and 215.8±0.92 μg/mL for T. nivea and T. claveryi, respectively.
format Article
author Elsayed, Elsayed Ahmed
Alsahli, F. D.
Barakat, Ibrahim Abdalla Hassan
El Enshasy, Hesham A.
Wadaan, M. A.
author_facet Elsayed, Elsayed Ahmed
Alsahli, F. D.
Barakat, Ibrahim Abdalla Hassan
El Enshasy, Hesham A.
Wadaan, M. A.
author_sort Elsayed, Elsayed Ahmed
title Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
title_short Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
title_full Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
title_fullStr Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
title_full_unstemmed Assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in Saudi Arabia
title_sort assessment of in vitro antimicrobial and anti-breast cancer activities of extracts isolated from desert truffles in saudi arabia
publisher Scientific Publishers
publishDate 2019
url http://eprints.utm.my/id/eprint/87684/1/HeshamAElEnshasy2019_AssessmentofInVitroAntimicrobialandAntiBreast.pdf
http://eprints.utm.my/id/eprint/87684/
http://nopr.niscair.res.in/handle/123456789/48789
_version_ 1685578973748133888
score 13.211869

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