Cover Image

Ionic liquid screening for solvent design of herbal phytochemical extraction

Ionic liquids (ILs) have been used in many applications and currently have been a favourable solvent in separation technology due to their solvation power compared to organic solvent. A development of IL solvent design approach is necessary in order to apply the most optimal solvents in herbal phyto...

Full description

Saved in:
Bibliographic Details
Main Authors: Rahman, N. R. H. A., Yunus, N. A., Mustaffa, A. A.
Format: Article
Published: Italian Association of Chemical Engineering - AIDIC 2017
Subjects:
TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/75512/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019447270&doi=10.3303%2fCET1756180&partnerID=40&md5=3a78e5486e8dc7eaa17563aac145a0d3
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.utm.75512
record_format eprints
spelling my.utm.755122018-03-29T00:47:34Z http://eprints.utm.my/id/eprint/75512/ Ionic liquid screening for solvent design of herbal phytochemical extraction Rahman, N. R. H. A. Yunus, N. A. Mustaffa, A. A. TP Chemical technology Ionic liquids (ILs) have been used in many applications and currently have been a favourable solvent in separation technology due to their solvation power compared to organic solvent. A development of IL solvent design approach is necessary in order to apply the most optimal solvents in herbal phytochemical extraction. In this study, solvent design utilised a systematic approach combined with property predictive model rather than trial-And-error experimental approach to reduce the amount of solvent waste and extraction time. This work focus on the screening of ILs as phytochemical extraction solvents of phenolic acids (e.g. gallic acid and caffeic acid) where we used property models of solubility and toxicity as part of solvent design. The methodology consisted of several stages. Stage 1 specifies the user needs of an extraction solvent, problems and constraints of new solvent design. Stage 2 involved in the development of a comprehensive Excel-based database of ionic liquid properties (e.g. solubility, heat capacity etc.) and factors that affect phytochemical extraction (e.g. extraction time, particle size etc.). In Stage 3, property library was assembled by collecting property models relevance for ILs from other studies to identify the most suitable models and estimate property values for solvent design. In Stage 4, ILs available in the database were first screened based on four factors: Toxicity, heat capacity, density and viscosity (properties which represent characteristics of solvent and which affect the extraction). Only those ILs which have acceptable value range of each properties were selected. Finally, the ILs candidates were further screened down based on their solvation performance by using a solubility parameter-solid-liquid equilibrium approach involving UNIFAC-IL models to select most optimal solvent that can extract highest amount of phytochemicals. From the screening process, 16 best IL solvent candidates for the phenolic acid extraction were obtained from a database of 880 imidazolium-based IL. Italian Association of Chemical Engineering - AIDIC 2017 Article PeerReviewed Rahman, N. R. H. A. and Yunus, N. A. and Mustaffa, A. A. (2017) Ionic liquid screening for solvent design of herbal phytochemical extraction. Chemical Engineering Transactions, 56 . pp. 1075-1080. ISSN 2283-9216 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019447270&doi=10.3303%2fCET1756180&partnerID=40&md5=3a78e5486e8dc7eaa17563aac145a0d3
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Rahman, N. R. H. A.
Yunus, N. A.
Mustaffa, A. A.
Ionic liquid screening for solvent design of herbal phytochemical extraction
description Ionic liquids (ILs) have been used in many applications and currently have been a favourable solvent in separation technology due to their solvation power compared to organic solvent. A development of IL solvent design approach is necessary in order to apply the most optimal solvents in herbal phytochemical extraction. In this study, solvent design utilised a systematic approach combined with property predictive model rather than trial-And-error experimental approach to reduce the amount of solvent waste and extraction time. This work focus on the screening of ILs as phytochemical extraction solvents of phenolic acids (e.g. gallic acid and caffeic acid) where we used property models of solubility and toxicity as part of solvent design. The methodology consisted of several stages. Stage 1 specifies the user needs of an extraction solvent, problems and constraints of new solvent design. Stage 2 involved in the development of a comprehensive Excel-based database of ionic liquid properties (e.g. solubility, heat capacity etc.) and factors that affect phytochemical extraction (e.g. extraction time, particle size etc.). In Stage 3, property library was assembled by collecting property models relevance for ILs from other studies to identify the most suitable models and estimate property values for solvent design. In Stage 4, ILs available in the database were first screened based on four factors: Toxicity, heat capacity, density and viscosity (properties which represent characteristics of solvent and which affect the extraction). Only those ILs which have acceptable value range of each properties were selected. Finally, the ILs candidates were further screened down based on their solvation performance by using a solubility parameter-solid-liquid equilibrium approach involving UNIFAC-IL models to select most optimal solvent that can extract highest amount of phytochemicals. From the screening process, 16 best IL solvent candidates for the phenolic acid extraction were obtained from a database of 880 imidazolium-based IL.
format Article
author Rahman, N. R. H. A.
Yunus, N. A.
Mustaffa, A. A.
author_facet Rahman, N. R. H. A.
Yunus, N. A.
Mustaffa, A. A.
author_sort Rahman, N. R. H. A.
title Ionic liquid screening for solvent design of herbal phytochemical extraction
title_short Ionic liquid screening for solvent design of herbal phytochemical extraction
title_full Ionic liquid screening for solvent design of herbal phytochemical extraction
title_fullStr Ionic liquid screening for solvent design of herbal phytochemical extraction
title_full_unstemmed Ionic liquid screening for solvent design of herbal phytochemical extraction
title_sort ionic liquid screening for solvent design of herbal phytochemical extraction
publisher Italian Association of Chemical Engineering - AIDIC
publishDate 2017
url http://eprints.utm.my/id/eprint/75512/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85019447270&doi=10.3303%2fCET1756180&partnerID=40&md5=3a78e5486e8dc7eaa17563aac145a0d3
_version_ 1643657084053487616
score 13.211869

Similar Items