New generation separation and identification methods for erythromycin

Erythromycin is an antibiotic which can effectively deal with a broad spectrum of Gram-positive bacterial pathogens and is usually used by people who have allergy to penicillin. During production of erythromycin, downstream processing contributes to a high portion of the production costs due to the...

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Main Authors: Chuo, S. C., Mohd. Setapar, S. H., Ahmad, A., Lokhat, D.
Format: Article
Published: Scholars Research Library 2016
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Online Access:http://eprints.utm.my/id/eprint/70052/
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spelling my.utm.700522017-11-22T00:45:09Z http://eprints.utm.my/id/eprint/70052/ New generation separation and identification methods for erythromycin Chuo, S. C. Mohd. Setapar, S. H. Ahmad, A. Lokhat, D. TA Engineering (General). Civil engineering (General) Erythromycin is an antibiotic which can effectively deal with a broad spectrum of Gram-positive bacterial pathogens and is usually used by people who have allergy to penicillin. During production of erythromycin, downstream processing contributes to a high portion of the production costs due to the nature of the broth. Conventional liquid-liquid extraction method has the problems of having limited choice of solvents and formation of emulsion which greatly hinders the separation process. Recently, various separation and purification alternatives can be found in literature such as pre-dispersed solvent extraction, ionic liquids, membrane filtration, liquid membrane, adsorption, and reverse micelle extraction. The improvements of downstream processing for antibiotics are necessary not only to enhance the quantity and quality of antibiotic products but also to improve the process itself to be more sustainable and environmental friendly. Scholars Research Library 2016 Article PeerReviewed Chuo, S. C. and Mohd. Setapar, S. H. and Ahmad, A. and Lokhat, D. (2016) New generation separation and identification methods for erythromycin. Der Pharmacia Lettre, 8 (19). pp. 215-222. ISSN 0975-5071 https://www.scopus.com
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TA Engineering (General). Civil engineering (General)
spellingShingle TA Engineering (General). Civil engineering (General)
Chuo, S. C.
Mohd. Setapar, S. H.
Ahmad, A.
Lokhat, D.
New generation separation and identification methods for erythromycin
description Erythromycin is an antibiotic which can effectively deal with a broad spectrum of Gram-positive bacterial pathogens and is usually used by people who have allergy to penicillin. During production of erythromycin, downstream processing contributes to a high portion of the production costs due to the nature of the broth. Conventional liquid-liquid extraction method has the problems of having limited choice of solvents and formation of emulsion which greatly hinders the separation process. Recently, various separation and purification alternatives can be found in literature such as pre-dispersed solvent extraction, ionic liquids, membrane filtration, liquid membrane, adsorption, and reverse micelle extraction. The improvements of downstream processing for antibiotics are necessary not only to enhance the quantity and quality of antibiotic products but also to improve the process itself to be more sustainable and environmental friendly.
format Article
author Chuo, S. C.
Mohd. Setapar, S. H.
Ahmad, A.
Lokhat, D.
author_facet Chuo, S. C.
Mohd. Setapar, S. H.
Ahmad, A.
Lokhat, D.
author_sort Chuo, S. C.
title New generation separation and identification methods for erythromycin
title_short New generation separation and identification methods for erythromycin
title_full New generation separation and identification methods for erythromycin
title_fullStr New generation separation and identification methods for erythromycin
title_full_unstemmed New generation separation and identification methods for erythromycin
title_sort new generation separation and identification methods for erythromycin
publisher Scholars Research Library
publishDate 2016
url http://eprints.utm.my/id/eprint/70052/
https://www.scopus.com
_version_ 1643656083792723968
score 13.211869