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Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties

The bioactive composite of hydroxyapatite and zeolite-ZSM5 was successfully synthesized via the cost effective microwave wet precipitation method. The structural and morphological features were studied by X-ray diffraction, FT-IR spectroscopy and TEM/EDX analysis. These tests revealed the presence o...

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Main Authors: Iqbal, Nida, Abdul Kadir, M. R., Iqbar, Saman, Abd. Razak, Saiful Izwan, Rafique, M. Shahid, Bakhsheshi-Rad, H. R., Idris, Mohd. Hasbullah, Khattak, M. A., Raghavendran, H. R. B., Abbas, A. A.
Format: Article
Published: Elsevier Ltd. 2016
Subjects:
QH426 Genetics
Online Access:http://eprints.utm.my/id/eprint/70041/
http://dx.doi.org/10.1016/j.ceramint.2016.01.107
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spelling my.utm.700412017-11-20T08:52:13Z http://eprints.utm.my/id/eprint/70041/ Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties Iqbal, Nida Abdul Kadir, M. R. Iqbar, Saman Abd. Razak, Saiful Izwan Rafique, M. Shahid Bakhsheshi-Rad, H. R. Idris, Mohd. Hasbullah Khattak, M. A. Raghavendran, H. R. B. Abbas, A. A. QH426 Genetics The bioactive composite of hydroxyapatite and zeolite-ZSM5 was successfully synthesized via the cost effective microwave wet precipitation method. The structural and morphological features were studied by X-ray diffraction, FT-IR spectroscopy and TEM/EDX analysis. These tests revealed the presence of zeolite and hydroxyapatite in the zeolite-HA composites. Spherical particles, 76-88±20 nm in size, were visible on the TEM. The simulated body fluid SBF results in vitro verified the ability of the composites to support and accelerate the growth of the HA. Furthermore, the MTT assay showed the viability of normal human osteoblasts (NHOst) on the composite, up to seven days of culture. The cell adhesion and proliferation of the normal human osteoblast (NHOst) cells onto the disc surface was much higher than the control. Overall, the ZSM-HA samples composite nanostructure can be a considered potential candidate for biomedical application. Elsevier Ltd. 2016 Article PeerReviewed Iqbal, Nida and Abdul Kadir, M. R. and Iqbar, Saman and Abd. Razak, Saiful Izwan and Rafique, M. Shahid and Bakhsheshi-Rad, H. R. and Idris, Mohd. Hasbullah and Khattak, M. A. and Raghavendran, H. R. B. and Abbas, A. A. (2016) Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties. Ceramics International, 42 (6). pp. 7175-7182. ISSN 0272-8842 http://dx.doi.org/10.1016/j.ceramint.2016.01.107 DOI:10.1016/j.ceramint.2016.01.107
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QH426 Genetics
spellingShingle QH426 Genetics
Iqbal, Nida
Abdul Kadir, M. R.
Iqbar, Saman
Abd. Razak, Saiful Izwan
Rafique, M. Shahid
Bakhsheshi-Rad, H. R.
Idris, Mohd. Hasbullah
Khattak, M. A.
Raghavendran, H. R. B.
Abbas, A. A.
Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
description The bioactive composite of hydroxyapatite and zeolite-ZSM5 was successfully synthesized via the cost effective microwave wet precipitation method. The structural and morphological features were studied by X-ray diffraction, FT-IR spectroscopy and TEM/EDX analysis. These tests revealed the presence of zeolite and hydroxyapatite in the zeolite-HA composites. Spherical particles, 76-88±20 nm in size, were visible on the TEM. The simulated body fluid SBF results in vitro verified the ability of the composites to support and accelerate the growth of the HA. Furthermore, the MTT assay showed the viability of normal human osteoblasts (NHOst) on the composite, up to seven days of culture. The cell adhesion and proliferation of the normal human osteoblast (NHOst) cells onto the disc surface was much higher than the control. Overall, the ZSM-HA samples composite nanostructure can be a considered potential candidate for biomedical application.
format Article
author Iqbal, Nida
Abdul Kadir, M. R.
Iqbar, Saman
Abd. Razak, Saiful Izwan
Rafique, M. Shahid
Bakhsheshi-Rad, H. R.
Idris, Mohd. Hasbullah
Khattak, M. A.
Raghavendran, H. R. B.
Abbas, A. A.
author_facet Iqbal, Nida
Abdul Kadir, M. R.
Iqbar, Saman
Abd. Razak, Saiful Izwan
Rafique, M. Shahid
Bakhsheshi-Rad, H. R.
Idris, Mohd. Hasbullah
Khattak, M. A.
Raghavendran, H. R. B.
Abbas, A. A.
author_sort Iqbal, Nida
title Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
title_short Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
title_full Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
title_fullStr Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
title_full_unstemmed Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties
title_sort nano-hydroxyapatite reinforced zeolite zsm composites: a comprehensive study on the structural and in vitro biological properties
publisher Elsevier Ltd.
publishDate 2016
url http://eprints.utm.my/id/eprint/70041/
http://dx.doi.org/10.1016/j.ceramint.2016.01.107
_version_ 1643656081447059456
score 13.211869

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