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Electrospinning applications from diagnosis to treatment of diabetes

Electrospinning is a facile, yet low cost and reproducible technique that can use both natural and synthetic polymers to address problems in diagnosis and treatment of diabetes. For the diagnosis of diabetes, effective continuous glucose monitoring of the blood glucose level can be achieved by using...

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Main Authors:	Vellayappan, M. V., Venugopal, J. R., Ramakrishna, S., Ray, S., Ismail, Ahmad Fauzi, Mandal, M., Manikandan, A., Seal, S., Jaganathan, S. K.
Format:	Article
Published:	Royal Society of Chemistry 2016
Subjects:	R Medicine (General)
Online Access:	http://eprints.utm.my/id/eprint/69365/ http://dx.doi.org/10.1039/c6ra15252j
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id	my.utm.69365
record_format	eprints
spelling	my.utm.693652017-11-22T00:45:15Z http://eprints.utm.my/id/eprint/69365/ Electrospinning applications from diagnosis to treatment of diabetes Vellayappan, M. V. Venugopal, J. R. Ramakrishna, S. Ray, S. Ismail, Ahmad Fauzi Mandal, M. Manikandan, A. Seal, S. Jaganathan, S. K. R Medicine (General) Electrospinning is a facile, yet low cost and reproducible technique that can use both natural and synthetic polymers to address problems in diagnosis and treatment of diabetes. For the diagnosis of diabetes, effective continuous glucose monitoring of the blood glucose level can be achieved by using electrospun glucose biosensors. Electrospun nanofibers confer a high-surface area, micro-porosity, and potential to encapsulate drugs or biomolecules within nanofibers. Even though electrospinning has been used widely there is no review available till now with the applications of electrospinning specifically for the diagnosis and treatment of diabetes. In this critical review, recent advances of electrospinning to optimize the glucose sensing ability and a myriad of diabetic drug delivery techniques via electrospinning are discussed. Future perspectives of biodegradable nanofibers are also discussed in the last section, which highlights the current challenges, innovation and development of novel electrospun nanofibers for theranostics targeted to diabetics. Royal Society of Chemistry 2016 Article PeerReviewed Vellayappan, M. V. and Venugopal, J. R. and Ramakrishna, S. and Ray, S. and Ismail, Ahmad Fauzi and Mandal, M. and Manikandan, A. and Seal, S. and Jaganathan, S. K. (2016) Electrospinning applications from diagnosis to treatment of diabetes. RSC Advances, 6 (87). pp. 83638-83655. ISSN 2046-2069 http://dx.doi.org/10.1039/c6ra15252j DOI:10.1039/c6ra15252j
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
topic	R Medicine (General)
spellingShingle	R Medicine (General) Vellayappan, M. V. Venugopal, J. R. Ramakrishna, S. Ray, S. Ismail, Ahmad Fauzi Mandal, M. Manikandan, A. Seal, S. Jaganathan, S. K. Electrospinning applications from diagnosis to treatment of diabetes
description	Electrospinning is a facile, yet low cost and reproducible technique that can use both natural and synthetic polymers to address problems in diagnosis and treatment of diabetes. For the diagnosis of diabetes, effective continuous glucose monitoring of the blood glucose level can be achieved by using electrospun glucose biosensors. Electrospun nanofibers confer a high-surface area, micro-porosity, and potential to encapsulate drugs or biomolecules within nanofibers. Even though electrospinning has been used widely there is no review available till now with the applications of electrospinning specifically for the diagnosis and treatment of diabetes. In this critical review, recent advances of electrospinning to optimize the glucose sensing ability and a myriad of diabetic drug delivery techniques via electrospinning are discussed. Future perspectives of biodegradable nanofibers are also discussed in the last section, which highlights the current challenges, innovation and development of novel electrospun nanofibers for theranostics targeted to diabetics.
format	Article
author	Vellayappan, M. V. Venugopal, J. R. Ramakrishna, S. Ray, S. Ismail, Ahmad Fauzi Mandal, M. Manikandan, A. Seal, S. Jaganathan, S. K.
author_facet	Vellayappan, M. V. Venugopal, J. R. Ramakrishna, S. Ray, S. Ismail, Ahmad Fauzi Mandal, M. Manikandan, A. Seal, S. Jaganathan, S. K.
author_sort	Vellayappan, M. V.
title	Electrospinning applications from diagnosis to treatment of diabetes
title_short	Electrospinning applications from diagnosis to treatment of diabetes
title_full	Electrospinning applications from diagnosis to treatment of diabetes
title_fullStr	Electrospinning applications from diagnosis to treatment of diabetes
title_full_unstemmed	Electrospinning applications from diagnosis to treatment of diabetes
title_sort	electrospinning applications from diagnosis to treatment of diabetes
publisher	Royal Society of Chemistry
publishDate	2016
url	http://eprints.utm.my/id/eprint/69365/ http://dx.doi.org/10.1039/c6ra15252j
_version_	1643656065165819904
score	13.211869

Electrospinning applications from diagnosis to treatment of diabetes

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