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Development and evaluation of nanoemulsion hydrogel

New methods of drug delivery can now be used to increase the effectiveness and safety of medication. Therefore, several new drug carrier systems have been developed such as nanoemulsions Nanoemulsion is submicron sized emulsion Typically in the range of 20-200 cm, Avocado oil is often used in herbal...

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Main Authors: Jaradat, Nidal A., Zaid, Abdel Nasir, Eid, Ahmad M., Elmarzugi, Nagib Ali
Format: Conference or Workshop Item
Published: 2015
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TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/63492/
http://www.pfmr.ps/?page_id=18
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spelling my.utm.634922017-05-30T05:04:38Z http://eprints.utm.my/id/eprint/63492/ Development and evaluation of nanoemulsion hydrogel Jaradat, Nidal A. Zaid, Abdel Nasir Eid, Ahmad M. Elmarzugi, Nagib Ali TP Chemical technology New methods of drug delivery can now be used to increase the effectiveness and safety of medication. Therefore, several new drug carrier systems have been developed such as nanoemulsions Nanoemulsion is submicron sized emulsion Typically in the range of 20-200 cm, Avocado oil is often used in herbal skin care. The aim of this study was to characterize nanoemulsion hydrogel prepared using avocado oil and sucrose ester stearate as surfactant. The nanoemulsion hydrogel were prepared by nanophase emulsification technique. These forrnulations were examined using zetasizer to determined the mean diameter of dispersed oil droplets, polydispersibility index (PD1) and zeta potential. Also the viscosity of the prepared nanoemulslon hydrogel were studied. The results reveled that nanoemulson prepared with 60% w/w oil, 24% w/w glycerol and 16%w/w surfactant showed droplets size below 200 nm with good polydispersibility index and zeta potential < -30 mV. The optimum formulation of nanoemulsion was prepared in the form of nanoemulsion hydrogel using cerbopols 934 and 940. The results of the viscometer for the nanoemulsion hydrogel showed that the storaqe modulus (G') which describes the elasticity of the component were greater than the loss modulus (G") values which reveals the viscosity of the component. 2015 Conference or Workshop Item PeerReviewed Jaradat, Nidal A. and Zaid, Abdel Nasir and Eid, Ahmad M. and Elmarzugi, Nagib Ali (2015) Development and evaluation of nanoemulsion hydrogel. In: Palestinian Forum for Medical Research Symposium, 4 Apr, 2015, Palestin. http://www.pfmr.ps/?page_id=18
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Jaradat, Nidal A.
Zaid, Abdel Nasir
Eid, Ahmad M.
Elmarzugi, Nagib Ali
Development and evaluation of nanoemulsion hydrogel
description New methods of drug delivery can now be used to increase the effectiveness and safety of medication. Therefore, several new drug carrier systems have been developed such as nanoemulsions Nanoemulsion is submicron sized emulsion Typically in the range of 20-200 cm, Avocado oil is often used in herbal skin care. The aim of this study was to characterize nanoemulsion hydrogel prepared using avocado oil and sucrose ester stearate as surfactant. The nanoemulsion hydrogel were prepared by nanophase emulsification technique. These forrnulations were examined using zetasizer to determined the mean diameter of dispersed oil droplets, polydispersibility index (PD1) and zeta potential. Also the viscosity of the prepared nanoemulslon hydrogel were studied. The results reveled that nanoemulson prepared with 60% w/w oil, 24% w/w glycerol and 16%w/w surfactant showed droplets size below 200 nm with good polydispersibility index and zeta potential < -30 mV. The optimum formulation of nanoemulsion was prepared in the form of nanoemulsion hydrogel using cerbopols 934 and 940. The results of the viscometer for the nanoemulsion hydrogel showed that the storaqe modulus (G') which describes the elasticity of the component were greater than the loss modulus (G") values which reveals the viscosity of the component.
format Conference or Workshop Item
author Jaradat, Nidal A.
Zaid, Abdel Nasir
Eid, Ahmad M.
Elmarzugi, Nagib Ali
author_facet Jaradat, Nidal A.
Zaid, Abdel Nasir
Eid, Ahmad M.
Elmarzugi, Nagib Ali
author_sort Jaradat, Nidal A.
title Development and evaluation of nanoemulsion hydrogel
title_short Development and evaluation of nanoemulsion hydrogel
title_full Development and evaluation of nanoemulsion hydrogel
title_fullStr Development and evaluation of nanoemulsion hydrogel
title_full_unstemmed Development and evaluation of nanoemulsion hydrogel
title_sort development and evaluation of nanoemulsion hydrogel
publishDate 2015
url http://eprints.utm.my/id/eprint/63492/
http://www.pfmr.ps/?page_id=18
_version_ 1643655731526762496
score 13.211869

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