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Technological advancements in characterizing single cell's stiffness properties- A review

Biophysical properties of living cells certainly play important roles for intra and intercellular biological events. However, conventional population approaches obscured cells heterogeneity and assume all cells are similar. With the introduction of single cell analysis, this limitation is slowly rec...

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Main Authors: Ahmad, I. L., Ahmad, M. R.
Format: Conference or Workshop Item
Published: 2015
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://eprints.utm.my/id/eprint/59497/
http://dx.doi.org/10.1109/IECBES.2014.7047483
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spelling my.utm.594972021-08-19T04:56:58Z http://eprints.utm.my/id/eprint/59497/ Technological advancements in characterizing single cell's stiffness properties- A review Ahmad, I. L. Ahmad, M. R. TK Electrical engineering. Electronics Nuclear engineering Biophysical properties of living cells certainly play important roles for intra and intercellular biological events. However, conventional population approaches obscured cells heterogeneity and assume all cells are similar. With the introduction of single cell analysis, this limitation is slowly rectified by defining crucial methods to further revealing cell-to-cell variability. Research in biomechanics leads to better elucidation of cellular and molecular changes due to disease progression i.e diseased cell exhibits different mechanical properties as compared to healthy ones. This paper highlights on various technological advancements available for single cell stiffness characterizations and analytical comparison of the reviewed methods will be thoroughly discussed. In addition, several applications intended for early disease detection were presented. 2015 Conference or Workshop Item PeerReviewed Ahmad, I. L. and Ahmad, M. R. (2015) Technological advancements in characterizing single cell's stiffness properties- A review. In: 3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014, 8 - 10December 2014, Kuala Lumpur, Malaysia. http://dx.doi.org/10.1109/IECBES.2014.7047483
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Ahmad, I. L.
Ahmad, M. R.
Technological advancements in characterizing single cell's stiffness properties- A review
description Biophysical properties of living cells certainly play important roles for intra and intercellular biological events. However, conventional population approaches obscured cells heterogeneity and assume all cells are similar. With the introduction of single cell analysis, this limitation is slowly rectified by defining crucial methods to further revealing cell-to-cell variability. Research in biomechanics leads to better elucidation of cellular and molecular changes due to disease progression i.e diseased cell exhibits different mechanical properties as compared to healthy ones. This paper highlights on various technological advancements available for single cell stiffness characterizations and analytical comparison of the reviewed methods will be thoroughly discussed. In addition, several applications intended for early disease detection were presented.
format Conference or Workshop Item
author Ahmad, I. L.
Ahmad, M. R.
author_facet Ahmad, I. L.
Ahmad, M. R.
author_sort Ahmad, I. L.
title Technological advancements in characterizing single cell's stiffness properties- A review
title_short Technological advancements in characterizing single cell's stiffness properties- A review
title_full Technological advancements in characterizing single cell's stiffness properties- A review
title_fullStr Technological advancements in characterizing single cell's stiffness properties- A review
title_full_unstemmed Technological advancements in characterizing single cell's stiffness properties- A review
title_sort technological advancements in characterizing single cell's stiffness properties- a review
publishDate 2015
url http://eprints.utm.my/id/eprint/59497/
http://dx.doi.org/10.1109/IECBES.2014.7047483
_version_ 1709667356493479936
score 13.211869

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