Magnetic resonance image segmentation for knee osteoarthritis using active shape models

Knee osteoarthritis is a chronic joint inflammation disease that affects the aged population nowadays. The disease leads to gradual degradation of cartilage and thus deteriorates the function of the knee joint. Magnetic Resonance Imaging (MRI) provides promising results for the early detection of kn...

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Main Authors: Soh, S. S., Tan, Tian Swee, Sim, Siew Ying, Chuah, Zhi En, Mazenan, M. N., Leong, Kah Meng
Format: Conference or Workshop Item
Published: 2015
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Online Access:http://eprints.utm.my/id/eprint/59361/
http://dx.doi.org/10.1109/BMEiCON.2014.7017365
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spelling my.utm.593612021-08-17T09:08:44Z http://eprints.utm.my/id/eprint/59361/ Magnetic resonance image segmentation for knee osteoarthritis using active shape models Soh, S. S. Tan, Tian Swee Sim, Siew Ying Chuah, Zhi En Mazenan, M. N. Leong, Kah Meng TP Chemical technology Knee osteoarthritis is a chronic joint inflammation disease that affects the aged population nowadays. The disease leads to gradual degradation of cartilage and thus deteriorates the function of the knee joint. Magnetic Resonance Imaging (MRI) provides promising results for the early detection of knee osteoarthritis. Conventionally, the MR image segmentation for knee osteoarthritis is manually done by clinicians. Limitations of this process include being laborious, time-consuming and prone to subjective diagnosis error. Therefore, the development of an automated cartilage segmentation method is crucial to assist the medical research in knee osteoarthritis. This project applied the Active Shape Models (ASM) approach to create semi-automated cartilage segmentation software. A shape model was constructed from a training set consisting of 10 knee MR images which includes major variations of the knee cartilage shape. Principle component analysis (PCA) was utilized to identify the main axes of variations used to build the shape model. This shape model was finally used to segment the knee articular cartilage. Outcomes of the ASM segmentation were compared with the outcome of manual segmentation. Experimental results showed that the sensitivity of developed ASM approach increased averagely from 73.78% to 80.75%, proportional to the increasing of the number of iteration in the segmentation as well as landmark of the shape model. This technique is reliable to contribute to medical research in knee osteoarthritis by providing an efficient and high accuracy segmentation method for knee articular cartilage, to further assist in the detection of knee osteoarthritis via MRI technique. 2015-01-20 Conference or Workshop Item PeerReviewed Soh, S. S. and Tan, Tian Swee and Sim, Siew Ying and Chuah, Zhi En and Mazenan, M. N. and Leong, Kah Meng (2015) Magnetic resonance image segmentation for knee osteoarthritis using active shape models. In: 7th Biomedical Engineering International Conference, BMEiCON 2014, 26 November 2014 - 28 November 2014, Fukuoka, Japan. http://dx.doi.org/10.1109/BMEiCON.2014.7017365
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Soh, S. S.
Tan, Tian Swee
Sim, Siew Ying
Chuah, Zhi En
Mazenan, M. N.
Leong, Kah Meng
Magnetic resonance image segmentation for knee osteoarthritis using active shape models
description Knee osteoarthritis is a chronic joint inflammation disease that affects the aged population nowadays. The disease leads to gradual degradation of cartilage and thus deteriorates the function of the knee joint. Magnetic Resonance Imaging (MRI) provides promising results for the early detection of knee osteoarthritis. Conventionally, the MR image segmentation for knee osteoarthritis is manually done by clinicians. Limitations of this process include being laborious, time-consuming and prone to subjective diagnosis error. Therefore, the development of an automated cartilage segmentation method is crucial to assist the medical research in knee osteoarthritis. This project applied the Active Shape Models (ASM) approach to create semi-automated cartilage segmentation software. A shape model was constructed from a training set consisting of 10 knee MR images which includes major variations of the knee cartilage shape. Principle component analysis (PCA) was utilized to identify the main axes of variations used to build the shape model. This shape model was finally used to segment the knee articular cartilage. Outcomes of the ASM segmentation were compared with the outcome of manual segmentation. Experimental results showed that the sensitivity of developed ASM approach increased averagely from 73.78% to 80.75%, proportional to the increasing of the number of iteration in the segmentation as well as landmark of the shape model. This technique is reliable to contribute to medical research in knee osteoarthritis by providing an efficient and high accuracy segmentation method for knee articular cartilage, to further assist in the detection of knee osteoarthritis via MRI technique.
format Conference or Workshop Item
author Soh, S. S.
Tan, Tian Swee
Sim, Siew Ying
Chuah, Zhi En
Mazenan, M. N.
Leong, Kah Meng
author_facet Soh, S. S.
Tan, Tian Swee
Sim, Siew Ying
Chuah, Zhi En
Mazenan, M. N.
Leong, Kah Meng
author_sort Soh, S. S.
title Magnetic resonance image segmentation for knee osteoarthritis using active shape models
title_short Magnetic resonance image segmentation for knee osteoarthritis using active shape models
title_full Magnetic resonance image segmentation for knee osteoarthritis using active shape models
title_fullStr Magnetic resonance image segmentation for knee osteoarthritis using active shape models
title_full_unstemmed Magnetic resonance image segmentation for knee osteoarthritis using active shape models
title_sort magnetic resonance image segmentation for knee osteoarthritis using active shape models
publishDate 2015
url http://eprints.utm.my/id/eprint/59361/
http://dx.doi.org/10.1109/BMEiCON.2014.7017365
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