Cover Image

Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics

Cancer is the second leading cause of mortality around the globe, despite the various advancements in science. The success of cancer treatment lies with early diagnosis and effective therapy making them inseparable. In recent years, there has been an extraordinary development in the field of nanomed...

Full description

Saved in:
Bibliographic Details
Main Authors: Subramanian, A. P., Jaganathan, S. K., Supriyanto, Eko
Format: Article
Published: Royal Society of Chemistry 2015
Subjects:
TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/58745/
http://dx.doi.org/10.1039/c5ra11912j
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.utm.58745
record_format eprints
spelling my.utm.587452021-08-19T06:13:27Z http://eprints.utm.my/id/eprint/58745/ Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics Subramanian, A. P. Jaganathan, S. K. Supriyanto, Eko TP Chemical technology Cancer is the second leading cause of mortality around the globe, despite the various advancements in science. The success of cancer treatment lies with early diagnosis and effective therapy making them inseparable. In recent years, there has been an extraordinary development in the field of nanomedicine with the development of new nanoparticles for the diagnosis and treatment of cancer. These studies are generally focused on creating novel nanocomposites for combating cancer. This review will serve as a one-stop arrangement for collating and providing future perspectives about the various nanocomposite based in vitro and in vivo investigations for cancer diagnosis and treatment. From our study, it is revealed that nanocomposite based diagnosis engrosses nanosensors for detection and conjugation of biomarkers, quantum dots, radiolabeling, delivery of contrast agent for better imaging of cancer development. In cancer therapeutics, nanocomposites hold enormous potential in maximizing the benefits of both targeted chemotherapy and photodynamic therapy. This review will encourage the need for in-depth molecular level examinations in relation to the cytotoxicity and bio-distribution of the developed nanocomposite should be evaluated in the clinical setting for better understanding. These supplementary studies on nanooncology would help in personalizing cancer theranostics making nanooncology a future trend. Royal Society of Chemistry 2015-08-11 Article PeerReviewed Subramanian, A. P. and Jaganathan, S. K. and Supriyanto, Eko (2015) Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics. Rsc Advances, 5 (89). pp. 72638-72652. ISSN 2046-2069 http://dx.doi.org/10.1039/c5ra11912j DOI:10.1039/c5ra11912j
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Subramanian, A. P.
Jaganathan, S. K.
Supriyanto, Eko
Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
description Cancer is the second leading cause of mortality around the globe, despite the various advancements in science. The success of cancer treatment lies with early diagnosis and effective therapy making them inseparable. In recent years, there has been an extraordinary development in the field of nanomedicine with the development of new nanoparticles for the diagnosis and treatment of cancer. These studies are generally focused on creating novel nanocomposites for combating cancer. This review will serve as a one-stop arrangement for collating and providing future perspectives about the various nanocomposite based in vitro and in vivo investigations for cancer diagnosis and treatment. From our study, it is revealed that nanocomposite based diagnosis engrosses nanosensors for detection and conjugation of biomarkers, quantum dots, radiolabeling, delivery of contrast agent for better imaging of cancer development. In cancer therapeutics, nanocomposites hold enormous potential in maximizing the benefits of both targeted chemotherapy and photodynamic therapy. This review will encourage the need for in-depth molecular level examinations in relation to the cytotoxicity and bio-distribution of the developed nanocomposite should be evaluated in the clinical setting for better understanding. These supplementary studies on nanooncology would help in personalizing cancer theranostics making nanooncology a future trend.
format Article
author Subramanian, A. P.
Jaganathan, S. K.
Supriyanto, Eko
author_facet Subramanian, A. P.
Jaganathan, S. K.
Supriyanto, Eko
author_sort Subramanian, A. P.
title Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
title_short Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
title_full Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
title_fullStr Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
title_full_unstemmed Overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
title_sort overview on in vitro and in vivo investigations of nanocomposite based cancer diagnosis and therapeutics
publisher Royal Society of Chemistry
publishDate 2015
url http://eprints.utm.my/id/eprint/58745/
http://dx.doi.org/10.1039/c5ra11912j
_version_ 1709667344297492480
score 13.211869

Similar Items