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Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method

Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design...

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Main Authors: Nallappan, Madana Leela, Nasef, Mohamad Mahmoud
Format: Article
Language:English
Published: Penerbit UTM Press 2015
Subjects:
TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf
http://eprints.utm.my/id/eprint/56195/
http://dx.doi.org/10.11113/jt.v75.5193
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spelling my.utm.561952017-11-01T04:16:56Z http://eprints.utm.my/id/eprint/56195/ Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method Nallappan, Madana Leela Nasef, Mohamad Mahmoud TP Chemical technology Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design were the applied electric voltage, the PVDF solution concentration, and the distance between the needle tip and the collecting drum. The Central Composite Design (CCD) was used to generate the experimental design whilst the analysis of variance (ANOVA) was performed to obtain statistical validation of regression models and to study the interaction between input parameters. The optimum operating conditions that guaranteed PVDF scaffolds with small nanofibre diameter were in the voltage and concentration range of 16-20 kV and 10-14wt%. Penerbit UTM Press 2015-01 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf Nallappan, Madana Leela and Nasef, Mohamad Mahmoud (2015) Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method. Jurnal Teknologi, 75 (6). pp. 103-107. ISSN 2180-3722 http://dx.doi.org/10.11113/jt.v75.5193 DOI:10.11113/jt.v75.5193
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Nallappan, Madana Leela
Nasef, Mohamad Mahmoud
Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
description Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design were the applied electric voltage, the PVDF solution concentration, and the distance between the needle tip and the collecting drum. The Central Composite Design (CCD) was used to generate the experimental design whilst the analysis of variance (ANOVA) was performed to obtain statistical validation of regression models and to study the interaction between input parameters. The optimum operating conditions that guaranteed PVDF scaffolds with small nanofibre diameter were in the voltage and concentration range of 16-20 kV and 10-14wt%.
format Article
author Nallappan, Madana Leela
Nasef, Mohamad Mahmoud
author_facet Nallappan, Madana Leela
Nasef, Mohamad Mahmoud
author_sort Nallappan, Madana Leela
title Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
title_short Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
title_full Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
title_fullStr Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
title_full_unstemmed Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
title_sort optimization of elecrospinning of pvdf scaffolds fabrication using response surface method
publisher Penerbit UTM Press
publishDate 2015
url http://eprints.utm.my/id/eprint/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf
http://eprints.utm.my/id/eprint/56195/
http://dx.doi.org/10.11113/jt.v75.5193
_version_ 1643654023385972736
score 13.211869

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