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Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals

Epilepsy is a chronic brain disorder that affects people all over the world. It is characterized by recurring seizures which are caused by sudden and brief excessive electrical discharges in the brain. Epileptic seizures are notoriously difficult to model due to their erratic behavior and limited av...

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Main Author: A. R. Ramachandran, Vinod
Format: Thesis
Language:English
Published: 2015
Subjects:
QA Mathematics
Online Access:http://eprints.utm.my/id/eprint/54924/1/VinodARRamachandranPFS2015.pdf
http://eprints.utm.my/id/eprint/54924/
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spelling my.utm.549242020-11-15T09:52:58Z http://eprints.utm.my/id/eprint/54924/ Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals A. R. Ramachandran, Vinod QA Mathematics Epilepsy is a chronic brain disorder that affects people all over the world. It is characterized by recurring seizures which are caused by sudden and brief excessive electrical discharges in the brain. Epileptic seizures are notoriously difficult to model due to their erratic behavior and limited availability of clean data to work with. In this research, an emulated probability measure called the Delia measure is developed to normalize raw EEG data before being mapped to the surface of a unit hypersphere and modeled using a von-Mises Fisher distribution. By computing the parameters for the distribution using genetic algorithms, it is determined that seizures can be sorted in order of their spread, which is an indicator of seizure violence. The Delia measure values are also used in conjunction with information theory to yield the self- information and entropy of seizures. Based on the information content obtained, a Type-2 fuzzy graph and a crisp graph are generated to describe the information flow and electrode interconnectivity respectively. These graphs show that there is a distinct difference between focal and generalized seizures, and that seizure data can be segregated into multiple communities. G¨odel’s incompleteness theorem is also used in conjunction with non-Euclidean geometry to prove that no two seizures are the same. Together, these results verify that there exists a governing pattern for epileptic seizures. 2015-11 Thesis NonPeerReviewed application/pdf en http://eprints.utm.my/id/eprint/54924/1/VinodARRamachandranPFS2015.pdf A. R. Ramachandran, Vinod (2015) Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals. PhD thesis, Universiti Teknologi Malaysia, Faculty of Science. http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:96701
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic QA Mathematics
spellingShingle QA Mathematics
A. R. Ramachandran, Vinod
Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
description Epilepsy is a chronic brain disorder that affects people all over the world. It is characterized by recurring seizures which are caused by sudden and brief excessive electrical discharges in the brain. Epileptic seizures are notoriously difficult to model due to their erratic behavior and limited availability of clean data to work with. In this research, an emulated probability measure called the Delia measure is developed to normalize raw EEG data before being mapped to the surface of a unit hypersphere and modeled using a von-Mises Fisher distribution. By computing the parameters for the distribution using genetic algorithms, it is determined that seizures can be sorted in order of their spread, which is an indicator of seizure violence. The Delia measure values are also used in conjunction with information theory to yield the self- information and entropy of seizures. Based on the information content obtained, a Type-2 fuzzy graph and a crisp graph are generated to describe the information flow and electrode interconnectivity respectively. These graphs show that there is a distinct difference between focal and generalized seizures, and that seizure data can be segregated into multiple communities. G¨odel’s incompleteness theorem is also used in conjunction with non-Euclidean geometry to prove that no two seizures are the same. Together, these results verify that there exists a governing pattern for epileptic seizures.
format Thesis
author A. R. Ramachandran, Vinod
author_facet A. R. Ramachandran, Vinod
author_sort A. R. Ramachandran, Vinod
title Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
title_short Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
title_full Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
title_fullStr Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
title_full_unstemmed Dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
title_sort dynamic epileptic activity analysis based on geometric structure of electroencephalographic signals
publishDate 2015
url http://eprints.utm.my/id/eprint/54924/1/VinodARRamachandranPFS2015.pdf
http://eprints.utm.my/id/eprint/54924/
http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:96701
_version_ 1684653442041118720
score 13.211869

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