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Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia

People affected with leukemia are on the rise and several strategies were employed to thwart this deadly disease. Recent decade of research focuses on phenolic constituents as a tool for combating various inflammatory, cancer, and cardiac diseases. Our research showed honey and its phenolic constitu...

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Main Authors: Jaganathan, Saravana Kumar, Mondhe, Dilip, Wani, Zahoor Ahmad, Supriyanto, Eko
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2014
Subjects:
RC Internal medicine
Online Access:http://eprints.utm.my/id/eprint/52768/1/SaravanaKumarJaganathan2014_Evaluationofselectedhoney.pdf
http://eprints.utm.my/id/eprint/52768/
http://dx.doi.org/10.1155/2014/912051
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spelling my.utm.527682018-06-30T00:48:13Z http://eprints.utm.my/id/eprint/52768/ Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia Jaganathan, Saravana Kumar Mondhe, Dilip Wani, Zahoor Ahmad Supriyanto, Eko RC Internal medicine People affected with leukemia are on the rise and several strategies were employed to thwart this deadly disease. Recent decade of research focuses on phenolic constituents as a tool for combating various inflammatory, cancer, and cardiac diseases. Our research showed honey and its phenolic constituents as crusaders against cancer. In this work, we explored the antileukemic activity of selected honey and one of its phenolic constituent eugenol against L1210 leukemia animal model. Results of this experiment showed that the selected honey samples as well as eugenol after intraperitoneal injection could not increase the median survival time (MST) of animals. Further, there was only slight marginal increase in the %T/C values of honey and eugenol treated groups. The number of phenolics present in the honey may not be a prime factor to promote antileukemic effect since there was no difference in the MST of two different honeys tested. This study limits the use of selected honey and eugenol against leukemia animal model. Hindawi Publishing Corporation 2014 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/52768/1/SaravanaKumarJaganathan2014_Evaluationofselectedhoney.pdf Jaganathan, Saravana Kumar and Mondhe, Dilip and Wani, Zahoor Ahmad and Supriyanto, Eko (2014) Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia. Scientific World Journal, 2014 . ISSN 2356-6140 http://dx.doi.org/10.1155/2014/912051 DOI: 10.1155/2014/912051
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic RC Internal medicine
spellingShingle RC Internal medicine
Jaganathan, Saravana Kumar
Mondhe, Dilip
Wani, Zahoor Ahmad
Supriyanto, Eko
Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
description People affected with leukemia are on the rise and several strategies were employed to thwart this deadly disease. Recent decade of research focuses on phenolic constituents as a tool for combating various inflammatory, cancer, and cardiac diseases. Our research showed honey and its phenolic constituents as crusaders against cancer. In this work, we explored the antileukemic activity of selected honey and one of its phenolic constituent eugenol against L1210 leukemia animal model. Results of this experiment showed that the selected honey samples as well as eugenol after intraperitoneal injection could not increase the median survival time (MST) of animals. Further, there was only slight marginal increase in the %T/C values of honey and eugenol treated groups. The number of phenolics present in the honey may not be a prime factor to promote antileukemic effect since there was no difference in the MST of two different honeys tested. This study limits the use of selected honey and eugenol against leukemia animal model.
format Article
author Jaganathan, Saravana Kumar
Mondhe, Dilip
Wani, Zahoor Ahmad
Supriyanto, Eko
author_facet Jaganathan, Saravana Kumar
Mondhe, Dilip
Wani, Zahoor Ahmad
Supriyanto, Eko
author_sort Jaganathan, Saravana Kumar
title Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
title_short Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
title_full Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
title_fullStr Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
title_full_unstemmed Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia
title_sort evaluation of selected honey and one of its phenolic constituent eugenol against l1210 lymphoid leukemia
publisher Hindawi Publishing Corporation
publishDate 2014
url http://eprints.utm.my/id/eprint/52768/1/SaravanaKumarJaganathan2014_Evaluationofselectedhoney.pdf
http://eprints.utm.my/id/eprint/52768/
http://dx.doi.org/10.1155/2014/912051
_version_ 1643653254226116608
score 13.211869

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