Staff View: Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques

Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques

A microfluidics-based device that has the capability to trap cells has been designed and constructed and its capabilities have been demonstrated using dielectrophoresis, a promising tool for the selective manipulation and separation of cells, bacteria and other bioparticles. The device consists of a...

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Main Authors:	Wee, W. H., Abdul Razak, Mohd. Azhar, Kadri, Nahrizul Adib
Format:	Article
Published:	2012
Subjects:	QD Chemistry
Online Access:	http://eprints.utm.my/id/eprint/46911/
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id	my.utm.46911
record_format	eprints
spelling	my.utm.469112017-09-26T07:58:41Z http://eprints.utm.my/id/eprint/46911/ Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques Wee, W. H. Abdul Razak, Mohd. Azhar Kadri, Nahrizul Adib QD Chemistry A microfluidics-based device that has the capability to trap cells has been designed and constructed and its capabilities have been demonstrated using dielectrophoresis, a promising tool for the selective manipulation and separation of cells, bacteria and other bioparticles. The device consists of a dielectrophoretic chamber and an interdigitated electrode geometry that is fabricated from gold-coated glass slides. It was designed with the intention of providing a device that was compatible with standard laboratory equipment and had the capability to prevent leakage and discriminate cells. Experimental results reveal that the device is capable of trapping leukemic K562 cells at an average efficiency of 94.2%. In addition to this, the design offers a number of advantages, which include the ability to exchange microscope slides and change separation chamber height. It is also reusable, easy to assembly and cleaning and provides a simple method of connecting electrodes and a power source. The device has the potential to become very beneficial in the preliminary stages of many immunosensing applications that require separation of different types of cells. 2012 Article PeerReviewed Wee, W. H. and Abdul Razak, Mohd. Azhar and Kadri, Nahrizul Adib (2012) Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques. International Journal of Electrochemical Science, 7 (11). pp. 11588-11595. ISSN 1452-3981
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
topic	QD Chemistry
spellingShingle	QD Chemistry Wee, W. H. Abdul Razak, Mohd. Azhar Kadri, Nahrizul Adib Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
description	A microfluidics-based device that has the capability to trap cells has been designed and constructed and its capabilities have been demonstrated using dielectrophoresis, a promising tool for the selective manipulation and separation of cells, bacteria and other bioparticles. The device consists of a dielectrophoretic chamber and an interdigitated electrode geometry that is fabricated from gold-coated glass slides. It was designed with the intention of providing a device that was compatible with standard laboratory equipment and had the capability to prevent leakage and discriminate cells. Experimental results reveal that the device is capable of trapping leukemic K562 cells at an average efficiency of 94.2%. In addition to this, the design offers a number of advantages, which include the ability to exchange microscope slides and change separation chamber height. It is also reusable, easy to assembly and cleaning and provides a simple method of connecting electrodes and a power source. The device has the potential to become very beneficial in the preliminary stages of many immunosensing applications that require separation of different types of cells.
format	Article
author	Wee, W. H. Abdul Razak, Mohd. Azhar Kadri, Nahrizul Adib
author_facet	Wee, W. H. Abdul Razak, Mohd. Azhar Kadri, Nahrizul Adib
author_sort	Wee, W. H.
title	Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
title_short	Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
title_full	Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
title_fullStr	Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
title_full_unstemmed	Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
title_sort	electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques
publishDate	2012
url	http://eprints.utm.my/id/eprint/46911/
_version_	1643652177380507648
score	13.211869

Electrochemical cell entrapment device for biomems applications using benchtop fabrication techniques

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