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InVitro characterization of antibacterial bioactive glass containing ceria

Several compositions of bioactive glass (BG) containing ceria were synthesized from chloride precursor using quick alkali sol–gel method. XRD data revealed the presence of ceria in 5 and 10 mol% Ce samples. SEM and EDX characterization confirmed the nano-size and elemental composition of all samples...

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Main Authors: Abdul Kadir, Mohammed Rafiq, Hussain, Rafaqat, Goh, Yi Fan, Alshemarya, Ammar Z., Muhammad Akram, Muhammad Akram
Format: Article
Published: Elsevier 2013
Subjects:
Q Science
Online Access:http://eprints.utm.my/id/eprint/40263/
https://doi.org/10.1016/j.ceramint.2013.06.062
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spelling my.utm.402632019-03-17T04:21:47Z http://eprints.utm.my/id/eprint/40263/ InVitro characterization of antibacterial bioactive glass containing ceria Abdul Kadir, Mohammed Rafiq Hussain, Rafaqat Goh, Yi Fan Alshemarya, Ammar Z. Muhammad Akram, Muhammad Akram Q Science Several compositions of bioactive glass (BG) containing ceria were synthesized from chloride precursor using quick alkali sol–gel method. XRD data revealed the presence of ceria in 5 and 10 mol% Ce samples. SEM and EDX characterization confirmed the nano-size and elemental composition of all samples, while FTIR data indicated that high Ce content has disrupted the silicate network of BG. UV absorption spectrum showed that ceria in BG samples is present in +3 and +4 oxidation states, depending on the initial cerium content. Nitrogen adsorption–desorption isotherm confirmed the mesoporosity of the samples. 5 and 10 mol% Ce samples exhibited significant antibacterial properties compared to 1Ce and 50Si samples. All samples induced the formation of apatite particles with Ca/P ratio close to 1.67 upon immersion in simulated body fluid (SBF), confirming their good bioactivity. For the first time, this study has demonstrated that cerium is a promising candidate to impart BG with excellent antibacterial properties without compromising its bioactivity. Elsevier 2013 Article PeerReviewed Abdul Kadir, Mohammed Rafiq and Hussain, Rafaqat and Goh, Yi Fan and Alshemarya, Ammar Z. and Muhammad Akram, Muhammad Akram (2013) InVitro characterization of antibacterial bioactive glass containing ceria. Ceramics International, 40 (n/a). pp. 729-737. ISSN 0272-8842 https://doi.org/10.1016/j.ceramint.2013.06.062 DOI:10.1016/j.ceramint.2013.06.062
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic Q Science
spellingShingle Q Science
Abdul Kadir, Mohammed Rafiq
Hussain, Rafaqat
Goh, Yi Fan
Alshemarya, Ammar Z.
Muhammad Akram, Muhammad Akram
InVitro characterization of antibacterial bioactive glass containing ceria
description Several compositions of bioactive glass (BG) containing ceria were synthesized from chloride precursor using quick alkali sol–gel method. XRD data revealed the presence of ceria in 5 and 10 mol% Ce samples. SEM and EDX characterization confirmed the nano-size and elemental composition of all samples, while FTIR data indicated that high Ce content has disrupted the silicate network of BG. UV absorption spectrum showed that ceria in BG samples is present in +3 and +4 oxidation states, depending on the initial cerium content. Nitrogen adsorption–desorption isotherm confirmed the mesoporosity of the samples. 5 and 10 mol% Ce samples exhibited significant antibacterial properties compared to 1Ce and 50Si samples. All samples induced the formation of apatite particles with Ca/P ratio close to 1.67 upon immersion in simulated body fluid (SBF), confirming their good bioactivity. For the first time, this study has demonstrated that cerium is a promising candidate to impart BG with excellent antibacterial properties without compromising its bioactivity.
format Article
author Abdul Kadir, Mohammed Rafiq
Hussain, Rafaqat
Goh, Yi Fan
Alshemarya, Ammar Z.
Muhammad Akram, Muhammad Akram
author_facet Abdul Kadir, Mohammed Rafiq
Hussain, Rafaqat
Goh, Yi Fan
Alshemarya, Ammar Z.
Muhammad Akram, Muhammad Akram
author_sort Abdul Kadir, Mohammed Rafiq
title InVitro characterization of antibacterial bioactive glass containing ceria
title_short InVitro characterization of antibacterial bioactive glass containing ceria
title_full InVitro characterization of antibacterial bioactive glass containing ceria
title_fullStr InVitro characterization of antibacterial bioactive glass containing ceria
title_full_unstemmed InVitro characterization of antibacterial bioactive glass containing ceria
title_sort invitro characterization of antibacterial bioactive glass containing ceria
publisher Elsevier
publishDate 2013
url http://eprints.utm.my/id/eprint/40263/
https://doi.org/10.1016/j.ceramint.2013.06.062
_version_ 1643650428468985856
score 13.244745

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