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Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzyme inhibition

The in vivo and in vitro mechanistic anti-inflammatory actions of cucurbitacin E (CE) (Citrullus lanatus var. citroides) were examined. The results showed that LPS/INF-? increased NO production in RAW264.7 macrophages, whereas L-NAME and CE curtailed it. CE did not reveal any cytotoxicity on RAW264....

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Bibliographic Details
Main Authors: Abdelwahab, Siddig Ibrahim, Hassan, Loiy Elsir Ahmed, Mohd. Sirat, Hasnah, Yagi, Sakina M. Ahmed, Koko, Waleed Syaed, Mohan, Syam Morali, Taha, Manal Mohamed Elhassan, Ahmad, Syahida, Cheah, Shiau Chuen, Narrima, Putri, Rais, Mohd. Mustafa, Abdul Hadi, Abdul Hamid
Format: Article
Published: Elsevier 2011
Subjects:
Q Science
Online Access:http://eprints.utm.my/id/eprint/28785/
http://dx.doi.org/10.1016/j.fitote.2011.08.002
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http://eprints.utm.my/id/eprint/28785/
http://dx.doi.org/10.1016/j.fitote.2011.08.002

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