Discovery of novel Coumarin-Schiff base hybrids as potential acetylcholinesterase inhibitors: design, synthesis, enzyme inhibition, and computational studies

To discover anti-acetylcholinesterase agents for the treatment of Alzheimer’s disease (AD), a series of novel Schiff base-coumarin hybrids was rationally designed, synthesized successfully, and structurally characterized using Fourier transform infrared (FTIR), Nuclear magnetic resonance (NMR), and...

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Main Authors: Hasan, Aso Hameed, Abdulrahman, Faruq Azeez, Obaidullah, Ahmad J., Alotaibi, Hadil Faris, Alanazi, Mohammed M., Noamaan, Mahmoud A., Murugesan, Sankaranarayanan, Amran, Syazwani Itri, Bhat, Ajmal R., Jamalis, Joazaizulfazli
Format: Article
Language:English
Published: MDPI 2023
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Online Access:http://eprints.utm.my/106207/1/SyazwaniItriAmran2023_DiscoveryofNovelCoumarinSchiffBase.pdf
http://eprints.utm.my/106207/
http://dx.doi.org/10.3390/ph16070971
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