Staff View: Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect

Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect

Plasmonic photothermal therapy (PPTT) by applying nanoparticles has attracted great attention as a new and effective adjuvant treatment for cancer in recent years. Ferromagnetic nanoparticles with good wavelength absorption in the infrared region are widely applied in the biomedicine field. In the p...

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Main Authors:	Sareh, Mosleh-Shirazi, Kasaee, Seyed Reza, Dehghani, Fatemehsadat, Kamyab, Hesam, Kirpichnikova, Irina, Chelliapan, Shreeshivadasan, Firuzyar, Tahereh, Akhtari, Mohammadreza, Mohammad Amani, Ali
Format:	Article
Published:	Elsevier Ltd 2023
Subjects:	T Technology (General)
Online Access:	http://eprints.utm.my/105862/ http://dx.doi.org/10.1016/j.ceramint.2022.11.329
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spelling	my.utm.1058622024-05-20T07:18:23Z http://eprints.utm.my/105862/ Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect Sareh, Mosleh-Shirazi Kasaee, Seyed Reza Dehghani, Fatemehsadat Kamyab, Hesam Kirpichnikova, Irina Chelliapan, Shreeshivadasan Firuzyar, Tahereh Akhtari, Mohammadreza Mohammad Amani, Ali T Technology (General) Plasmonic photothermal therapy (PPTT) by applying nanoparticles has attracted great attention as a new and effective adjuvant treatment for cancer in recent years. Ferromagnetic nanoparticles with good wavelength absorption in the infrared region are widely applied in the biomedicine field. In the present study, the CoFe2O4 and -ZnFe2O4 NPs were performed by applying Rutin extract, as a non-invasive and green synthesis method, for PPTT of MCF-7 breast cancer cells. Physical and structural characteristics were studied by using a Transmission electron microscope (TEM), Energy Dispersive X-Ray Analysis (EDX), Scanning electron microscope (SEM), Vibrating sample magnetometer (VSM) analysis, X-Ray Diffraction (XRD), and the Fourier-Transform Infrared (FTIR) spectroscopy. Microscopic images confirmed a spherical shape with an average size of 29 and 25 nm for biosynthesized CoFe2O4 and ZnFe2O4 nanoparticles, respectively. It is also revealed that the biosynthesized CoFe2O4 and ZnFe2O4 nanoparticles exhibit ferromagnetic and superparamagnetic behavior, with saturation magnetization of 56.2 and 6 emu/g, respectively. Therefore, these nanoparticles revealed excellent and effective magnetic characteristics as an important factor in magnetic hyperthermia therapeutic applications. The results of the MTT assay and inverted stage microscope revealed significant photothermal efficacy of green synthesized CoFe2O4 and ZnFe2O4 nanoparticles combined with laser radiation against MCF-7 cells, however, this effect is more prominent for CoFe2O4 nanoparticles. MTT investigation proved the low and acceptable toxicity of these nanoparticles for normal cells as a critical parameter for biological applications. Elsevier Ltd 2023 Article PeerReviewed Sareh, Mosleh-Shirazi and Kasaee, Seyed Reza and Dehghani, Fatemehsadat and Kamyab, Hesam and Kirpichnikova, Irina and Chelliapan, Shreeshivadasan and Firuzyar, Tahereh and Akhtari, Mohammadreza and Mohammad Amani, Ali (2023) Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect. Ceramics International, 49 (7). pp. 11293-11301. ISSN 0272-8842 http://dx.doi.org/10.1016/j.ceramint.2022.11.329 DOI : 10.1016/j.ceramint.2022.11.329
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
topic	T Technology (General)
spellingShingle	T Technology (General) Sareh, Mosleh-Shirazi Kasaee, Seyed Reza Dehghani, Fatemehsadat Kamyab, Hesam Kirpichnikova, Irina Chelliapan, Shreeshivadasan Firuzyar, Tahereh Akhtari, Mohammadreza Mohammad Amani, Ali Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
description	Plasmonic photothermal therapy (PPTT) by applying nanoparticles has attracted great attention as a new and effective adjuvant treatment for cancer in recent years. Ferromagnetic nanoparticles with good wavelength absorption in the infrared region are widely applied in the biomedicine field. In the present study, the CoFe2O4 and -ZnFe2O4 NPs were performed by applying Rutin extract, as a non-invasive and green synthesis method, for PPTT of MCF-7 breast cancer cells. Physical and structural characteristics were studied by using a Transmission electron microscope (TEM), Energy Dispersive X-Ray Analysis (EDX), Scanning electron microscope (SEM), Vibrating sample magnetometer (VSM) analysis, X-Ray Diffraction (XRD), and the Fourier-Transform Infrared (FTIR) spectroscopy. Microscopic images confirmed a spherical shape with an average size of 29 and 25 nm for biosynthesized CoFe2O4 and ZnFe2O4 nanoparticles, respectively. It is also revealed that the biosynthesized CoFe2O4 and ZnFe2O4 nanoparticles exhibit ferromagnetic and superparamagnetic behavior, with saturation magnetization of 56.2 and 6 emu/g, respectively. Therefore, these nanoparticles revealed excellent and effective magnetic characteristics as an important factor in magnetic hyperthermia therapeutic applications. The results of the MTT assay and inverted stage microscope revealed significant photothermal efficacy of green synthesized CoFe2O4 and ZnFe2O4 nanoparticles combined with laser radiation against MCF-7 cells, however, this effect is more prominent for CoFe2O4 nanoparticles. MTT investigation proved the low and acceptable toxicity of these nanoparticles for normal cells as a critical parameter for biological applications.
format	Article
author	Sareh, Mosleh-Shirazi Kasaee, Seyed Reza Dehghani, Fatemehsadat Kamyab, Hesam Kirpichnikova, Irina Chelliapan, Shreeshivadasan Firuzyar, Tahereh Akhtari, Mohammadreza Mohammad Amani, Ali
author_facet	Sareh, Mosleh-Shirazi Kasaee, Seyed Reza Dehghani, Fatemehsadat Kamyab, Hesam Kirpichnikova, Irina Chelliapan, Shreeshivadasan Firuzyar, Tahereh Akhtari, Mohammadreza Mohammad Amani, Ali
author_sort	Sareh, Mosleh-Shirazi
title	Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
title_short	Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
title_full	Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
title_fullStr	Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
title_full_unstemmed	Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
title_sort	investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect
publisher	Elsevier Ltd
publishDate	2023
url	http://eprints.utm.my/105862/ http://dx.doi.org/10.1016/j.ceramint.2022.11.329
_version_	1800082673761255424
score	13.211869

Investigation through the anticancer properties of green synthesized spinel ferrite nanoparticles in present and absent of laser photothermal effect

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