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Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments

The biodegradation behavior of newly developed orthopedic implant materials provides essential insight into the potential degradation products and their ability to match the rate of bone healing prior to complete degradation. Ironically, biodegradation performance is not only influenced by alloy des...

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Main Authors: Shafyra, Sabri, Engku Abu Bakar, Engku Mohammad Nazim, Ngadiman, Nor Hasrul Akhmal, Sudin, Izman
Format: Article
Language:English
Published: MDPI 2023
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://eprints.utm.my/105780/1/NorHasrulAkhmal2023_ComparativeStudyontheMicrostructureandBiodegradation.pdf
http://eprints.utm.my/105780/
http://dx.doi.org/10.3390/met13010136
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spelling my.utm.1057802024-05-18T01:44:28Z http://eprints.utm.my/105780/ Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments Shafyra, Sabri Engku Abu Bakar, Engku Mohammad Nazim Ngadiman, Nor Hasrul Akhmal Sudin, Izman TJ Mechanical engineering and machinery The biodegradation behavior of newly developed orthopedic implant materials provides essential insight into the potential degradation products and their ability to match the rate of bone healing prior to complete degradation. Ironically, biodegradation performance is not only influenced by alloy design or advanced surface treatment on the alloy, but also it is dominantly controlled by the specific inorganic species and their concentration in the corrosion media as well as their pH level. In this study, the biodegradation behavior of commercially pure magnesium (CP Mg) and a Mg-1.0Ca-0.5Sr alloy was evaluated in 27 mM (Formula presented.) - Simulated Body Fluid (r-SBF) due to its identical ionic species and concentrations with human blood plasma via immersion test, including (i) hydrogen evolution test (H2), (ii) pH trend, and (iii) weight-loss measurement. To simulate the pH regulation by the physiological homeostatic response, the pseudo-physiological solution was treated with two treatments: through a (i) a 24 h corrosion media renewal routine and through the use of (ii) a TRIS-HCL buffer reagent. The Mg-1.0Ca-0.5Sr alloy is shown to have superior corrosion resistance due to grain refinement and unique secondary phases, whereas the daily renewal routine imparts a better emulation of in vivo corrosion control. MDPI 2023-01 Article PeerReviewed application/pdf en http://eprints.utm.my/105780/1/NorHasrulAkhmal2023_ComparativeStudyontheMicrostructureandBiodegradation.pdf Shafyra, Sabri and Engku Abu Bakar, Engku Mohammad Nazim and Ngadiman, Nor Hasrul Akhmal and Sudin, Izman (2023) Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments. Metals, 13 (1). pp. 1-21. ISSN 2075-4701 http://dx.doi.org/10.3390/met13010136 DOI:10.3390/met13010136
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Shafyra, Sabri
Engku Abu Bakar, Engku Mohammad Nazim
Ngadiman, Nor Hasrul Akhmal
Sudin, Izman
Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
description The biodegradation behavior of newly developed orthopedic implant materials provides essential insight into the potential degradation products and their ability to match the rate of bone healing prior to complete degradation. Ironically, biodegradation performance is not only influenced by alloy design or advanced surface treatment on the alloy, but also it is dominantly controlled by the specific inorganic species and their concentration in the corrosion media as well as their pH level. In this study, the biodegradation behavior of commercially pure magnesium (CP Mg) and a Mg-1.0Ca-0.5Sr alloy was evaluated in 27 mM (Formula presented.) - Simulated Body Fluid (r-SBF) due to its identical ionic species and concentrations with human blood plasma via immersion test, including (i) hydrogen evolution test (H2), (ii) pH trend, and (iii) weight-loss measurement. To simulate the pH regulation by the physiological homeostatic response, the pseudo-physiological solution was treated with two treatments: through a (i) a 24 h corrosion media renewal routine and through the use of (ii) a TRIS-HCL buffer reagent. The Mg-1.0Ca-0.5Sr alloy is shown to have superior corrosion resistance due to grain refinement and unique secondary phases, whereas the daily renewal routine imparts a better emulation of in vivo corrosion control.
format Article
author Shafyra, Sabri
Engku Abu Bakar, Engku Mohammad Nazim
Ngadiman, Nor Hasrul Akhmal
Sudin, Izman
author_facet Shafyra, Sabri
Engku Abu Bakar, Engku Mohammad Nazim
Ngadiman, Nor Hasrul Akhmal
Sudin, Izman
author_sort Shafyra, Sabri
title Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
title_short Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
title_full Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
title_fullStr Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
title_full_unstemmed Comparative study on the microstructure and biodegradation behavior of commercialized pure Mg and Mg-1.0Ca-0.5Sr alloy in 27 mM HCO3−-SBF: the influence of the pH regulation treatments
title_sort comparative study on the microstructure and biodegradation behavior of commercialized pure mg and mg-1.0ca-0.5sr alloy in 27 mm hco3−-sbf: the influence of the ph regulation treatments
publisher MDPI
publishDate 2023
url http://eprints.utm.my/105780/1/NorHasrulAkhmal2023_ComparativeStudyontheMicrostructureandBiodegradation.pdf
http://eprints.utm.my/105780/
http://dx.doi.org/10.3390/met13010136
_version_ 1800082662433488896
score 13.211869

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