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Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application

Although wound dressings are essential to protect wound from infection, these wound care products have limited function in facilitating wound healing. This study aimed to synthesize multi-walled carbon nanotube (MWCNT)/quercetin (QUE)/chitosan (CS) blended composite membrane and analyze their physic...

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Main Authors: Baktehir, Nurul Huda, Mohamed Arbi, Mohamad Ajma’in, Selvaras, Thiviya, Ismail, Norjihada Izzah
Format: Article
Language:English
Published: Penerbit UTM Press 2023
Subjects:
Q Science (General)
Online Access:http://eprints.utm.my/105308/1/NorjihadaIzzahIsmail2023_BlendofMultiWalledCarbonNanotubes.pdf
http://eprints.utm.my/105308/
http://dx.doi.org/10.11113/mjfas.v19n2.2776
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spelling my.utm.1053082024-04-22T10:25:10Z http://eprints.utm.my/105308/ Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application Baktehir, Nurul Huda Mohamed Arbi, Mohamad Ajma’in Selvaras, Thiviya Ismail, Norjihada Izzah Q Science (General) Although wound dressings are essential to protect wound from infection, these wound care products have limited function in facilitating wound healing. This study aimed to synthesize multi-walled carbon nanotube (MWCNT)/quercetin (QUE)/chitosan (CS) blended composite membrane and analyze their physicochemical properties for wound dressing application in comparison to the pure chitosan (CS) membrane. The MWCNT/QUE/CS blended membranes were prepared by mixing CS, QUE and MWCNT at a ratio of 3:1:1 using a solvent casting method. The membranes were analyzed physicochemically for their surface morphology, elemental composition, structural composition, wettability, water vapor transmission rate (WVTR) and swelling properties and were compared to the pure CS membrane. The findings pointed out that the blend of MWCNTs and QUE in the CS matrix produces a membrane with uneven and more hydrophilic surface with water contact angle of 64.70°± 3.7 and low WVTR of 16.26 g/m2.day after 24 h. The swelling analysis showed that the blended membrane was able to absorb more than 60% of water within 10 minutes, although lower than the pure CS membrane. This study revealed that MWCNT/QUE/CS blended membrane could possibly be used as a wound dressing as it may promote moist environment needed for wound healing in addition to its antibacterial and antioxidant properties that may accelerate wound healing process. Penerbit UTM Press 2023-03 Article PeerReviewed application/pdf en http://eprints.utm.my/105308/1/NorjihadaIzzahIsmail2023_BlendofMultiWalledCarbonNanotubes.pdf Baktehir, Nurul Huda and Mohamed Arbi, Mohamad Ajma’in and Selvaras, Thiviya and Ismail, Norjihada Izzah (2023) Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application. Malaysian Journal of Fundamental and Applied Sciences, 19 (2). pp. 202-214. ISSN 2289-599X http://dx.doi.org/10.11113/mjfas.v19n2.2776 DOI:10.11113/mjfas.v19n2.2776
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Baktehir, Nurul Huda
Mohamed Arbi, Mohamad Ajma’in
Selvaras, Thiviya
Ismail, Norjihada Izzah
Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
description Although wound dressings are essential to protect wound from infection, these wound care products have limited function in facilitating wound healing. This study aimed to synthesize multi-walled carbon nanotube (MWCNT)/quercetin (QUE)/chitosan (CS) blended composite membrane and analyze their physicochemical properties for wound dressing application in comparison to the pure chitosan (CS) membrane. The MWCNT/QUE/CS blended membranes were prepared by mixing CS, QUE and MWCNT at a ratio of 3:1:1 using a solvent casting method. The membranes were analyzed physicochemically for their surface morphology, elemental composition, structural composition, wettability, water vapor transmission rate (WVTR) and swelling properties and were compared to the pure CS membrane. The findings pointed out that the blend of MWCNTs and QUE in the CS matrix produces a membrane with uneven and more hydrophilic surface with water contact angle of 64.70°± 3.7 and low WVTR of 16.26 g/m2.day after 24 h. The swelling analysis showed that the blended membrane was able to absorb more than 60% of water within 10 minutes, although lower than the pure CS membrane. This study revealed that MWCNT/QUE/CS blended membrane could possibly be used as a wound dressing as it may promote moist environment needed for wound healing in addition to its antibacterial and antioxidant properties that may accelerate wound healing process.
format Article
author Baktehir, Nurul Huda
Mohamed Arbi, Mohamad Ajma’in
Selvaras, Thiviya
Ismail, Norjihada Izzah
author_facet Baktehir, Nurul Huda
Mohamed Arbi, Mohamad Ajma’in
Selvaras, Thiviya
Ismail, Norjihada Izzah
author_sort Baktehir, Nurul Huda
title Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
title_short Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
title_full Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
title_fullStr Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
title_full_unstemmed Blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
title_sort blend of multi-walled carbon nanotubes and quercetin improves physicochemical properties of chitosan membrane for wound dressing application
publisher Penerbit UTM Press
publishDate 2023
url http://eprints.utm.my/105308/1/NorjihadaIzzahIsmail2023_BlendofMultiWalledCarbonNanotubes.pdf
http://eprints.utm.my/105308/
http://dx.doi.org/10.11113/mjfas.v19n2.2776
_version_ 1797905994523607040
score 13.211869

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