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Recent modifications of carbon nanotubes for biomedical applications

Recent advances in the biomedical field have been remarkably achieved in the last few years, especially in the fabrication of nanomaterials that have various applications. Carbon nanotubes (CNTs) are carbon-based materials with cylindrical shapes that have an average diameter of less than 2 nanometr...

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Main Authors:	Mohd. Hatta, Mohd. Hayrie, Matmin, Juan, Ghazalli, Nur Fatiha, Abd. Khadir Jalani, Mohamad Azani, Hussin, Faisal
Format:	Article
Language:	English
Published:	Penerbit UTM Press 2023
Subjects:	QD Chemistry
Online Access:	http://eprints.utm.my/105177/1/JuanMatmin2023_RecentModificationsofCarbonNanotubes.pdf http://eprints.utm.my/105177/ http://dx.doi.org/10.11113/jurnalteknologi.v85.19253
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spelling	my.utm.1051772024-04-07T04:12:23Z http://eprints.utm.my/105177/ Recent modifications of carbon nanotubes for biomedical applications Mohd. Hatta, Mohd. Hayrie Matmin, Juan Ghazalli, Nur Fatiha Abd. Khadir Jalani, Mohamad Azani Hussin, Faisal QD Chemistry Recent advances in the biomedical field have been remarkably achieved in the last few years, especially in the fabrication of nanomaterials that have various applications. Carbon nanotubes (CNTs) are carbon-based materials with cylindrical shapes that have an average diameter of less than 2 nanometre (nm) for single-walled CNTs (SWCNTs) and an average diameter up to 100 nm for multi-walled CNTs (MWCNTs). CNTs demonstrate unique chemical, physical and electronic properties, and these remarkable properties have led to the development of CNTs-based materials in the biomedical field. For the past decades, the functionalization of CNTs has been actively developed to increase their biocompatibility for application in antibacterial materials, dentistry, drug delivery, and biosensing. The surface functionalization enhances the capabilities, features, and properties by modifying the surface chemistry of CNTs to improve their biocompatibility. The functionalization of CNTs will enable the biomolecule loading on the surface of CNTs, and thus can be used for drug delivery for targeted cells or immobilization support. This review discusses the related literature on biomedical applications of CNTs such as antibacterial, dental materials, cancer therapy and biosensors from 2007 – 2022. We also review the antibacterial properties between SWCNTs and MWCNTs, functionalized CNTs reinforced nanocomposite for dental applications, and the ability of CNTs to work as nanocarriers to deliver drugs directly to cancer cells. Moreover, the applications of CNTs-based biosensors in detecting biological and biomedical compounds are also discussed. This review is expected to provide guidelines for developing CNTs-based materials in the applications of biomedical field. Penerbit UTM Press 2023-03 Article PeerReviewed application/pdf en http://eprints.utm.my/105177/1/JuanMatmin2023_RecentModificationsofCarbonNanotubes.pdf Mohd. Hatta, Mohd. Hayrie and Matmin, Juan and Ghazalli, Nur Fatiha and Abd. Khadir Jalani, Mohamad Azani and Hussin, Faisal (2023) Recent modifications of carbon nanotubes for biomedical applications. Jurnal Teknologi, 85 (2). pp. 83-100. ISSN 0127-9696 http://dx.doi.org/10.11113/jurnalteknologi.v85.19253 DOI:10.11113/jurnalteknologi.v85.19253
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Mohd. Hatta, Mohd. Hayrie Matmin, Juan Ghazalli, Nur Fatiha Abd. Khadir Jalani, Mohamad Azani Hussin, Faisal Recent modifications of carbon nanotubes for biomedical applications
description	Recent advances in the biomedical field have been remarkably achieved in the last few years, especially in the fabrication of nanomaterials that have various applications. Carbon nanotubes (CNTs) are carbon-based materials with cylindrical shapes that have an average diameter of less than 2 nanometre (nm) for single-walled CNTs (SWCNTs) and an average diameter up to 100 nm for multi-walled CNTs (MWCNTs). CNTs demonstrate unique chemical, physical and electronic properties, and these remarkable properties have led to the development of CNTs-based materials in the biomedical field. For the past decades, the functionalization of CNTs has been actively developed to increase their biocompatibility for application in antibacterial materials, dentistry, drug delivery, and biosensing. The surface functionalization enhances the capabilities, features, and properties by modifying the surface chemistry of CNTs to improve their biocompatibility. The functionalization of CNTs will enable the biomolecule loading on the surface of CNTs, and thus can be used for drug delivery for targeted cells or immobilization support. This review discusses the related literature on biomedical applications of CNTs such as antibacterial, dental materials, cancer therapy and biosensors from 2007 – 2022. We also review the antibacterial properties between SWCNTs and MWCNTs, functionalized CNTs reinforced nanocomposite for dental applications, and the ability of CNTs to work as nanocarriers to deliver drugs directly to cancer cells. Moreover, the applications of CNTs-based biosensors in detecting biological and biomedical compounds are also discussed. This review is expected to provide guidelines for developing CNTs-based materials in the applications of biomedical field.
format	Article
author	Mohd. Hatta, Mohd. Hayrie Matmin, Juan Ghazalli, Nur Fatiha Abd. Khadir Jalani, Mohamad Azani Hussin, Faisal
author_facet	Mohd. Hatta, Mohd. Hayrie Matmin, Juan Ghazalli, Nur Fatiha Abd. Khadir Jalani, Mohamad Azani Hussin, Faisal
author_sort	Mohd. Hatta, Mohd. Hayrie
title	Recent modifications of carbon nanotubes for biomedical applications
title_short	Recent modifications of carbon nanotubes for biomedical applications
title_full	Recent modifications of carbon nanotubes for biomedical applications
title_fullStr	Recent modifications of carbon nanotubes for biomedical applications
title_full_unstemmed	Recent modifications of carbon nanotubes for biomedical applications
title_sort	recent modifications of carbon nanotubes for biomedical applications
publisher	Penerbit UTM Press
publishDate	2023
url	http://eprints.utm.my/105177/1/JuanMatmin2023_RecentModificationsofCarbonNanotubes.pdf http://eprints.utm.my/105177/ http://dx.doi.org/10.11113/jurnalteknologi.v85.19253
_version_	1797905955609903104
score	13.211869

Recent modifications of carbon nanotubes for biomedical applications

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