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Fungal morphology: a challenge in bioprocess engineering industries for product development

Fungal biofactories are well established in bioprocess industries. They have been used for the production of essential biomolecules in chemical, food, and pharmaceutical industries. The high growth rate and the ability of fungal cells to hydrolyze wide range of complex and economic substrates make t...

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Main Author: El-Enshasy, Hesham Ali Metwally Ali
Format: Article
Published: Elsevier Ltd 2022
Subjects:
TP Chemical technology
Online Access:http://eprints.utm.my/103473/
http://dx.doi.org/10.1016/j.coche.2021.100729
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spelling my.utm.1034732023-11-14T06:14:52Z http://eprints.utm.my/103473/ Fungal morphology: a challenge in bioprocess engineering industries for product development El-Enshasy, Hesham Ali Metwally Ali TP Chemical technology Fungal biofactories are well established in bioprocess industries. They have been used for the production of essential biomolecules in chemical, food, and pharmaceutical industries. The high growth rate and the ability of fungal cells to hydrolyze wide range of complex and economic substrates make them among the superior microorganism for large scale production. In addition, they have high capacity for product excretion in high concentration which reduces the overall throughput of the production process and reduces the downstream cost as well. However, growth morphology in submerged culture is one of the greatest challenges in bioprocess industries. The same strain can exhibit extremely different morphologies with any minor alteration in cultivation conditions or medium composition, and thus affect the product yield. In this review, we present the fungal morphology in a complete and full-scale approach from spore induction in hyphal cells up to complete biopellet formation. Elsevier Ltd 2022 Article PeerReviewed El-Enshasy, Hesham Ali Metwally Ali (2022) Fungal morphology: a challenge in bioprocess engineering industries for product development. Current Opinion in Chemical Engineering, 35 (NA). pp. 1-11. ISSN 2211-3398 http://dx.doi.org/10.1016/j.coche.2021.100729 DOI : 10.1016/j.coche.2021.100729
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
El-Enshasy, Hesham Ali Metwally Ali
Fungal morphology: a challenge in bioprocess engineering industries for product development
description Fungal biofactories are well established in bioprocess industries. They have been used for the production of essential biomolecules in chemical, food, and pharmaceutical industries. The high growth rate and the ability of fungal cells to hydrolyze wide range of complex and economic substrates make them among the superior microorganism for large scale production. In addition, they have high capacity for product excretion in high concentration which reduces the overall throughput of the production process and reduces the downstream cost as well. However, growth morphology in submerged culture is one of the greatest challenges in bioprocess industries. The same strain can exhibit extremely different morphologies with any minor alteration in cultivation conditions or medium composition, and thus affect the product yield. In this review, we present the fungal morphology in a complete and full-scale approach from spore induction in hyphal cells up to complete biopellet formation.
format Article
author El-Enshasy, Hesham Ali Metwally Ali
author_facet El-Enshasy, Hesham Ali Metwally Ali
author_sort El-Enshasy, Hesham Ali Metwally Ali
title Fungal morphology: a challenge in bioprocess engineering industries for product development
title_short Fungal morphology: a challenge in bioprocess engineering industries for product development
title_full Fungal morphology: a challenge in bioprocess engineering industries for product development
title_fullStr Fungal morphology: a challenge in bioprocess engineering industries for product development
title_full_unstemmed Fungal morphology: a challenge in bioprocess engineering industries for product development
title_sort fungal morphology: a challenge in bioprocess engineering industries for product development
publisher Elsevier Ltd
publishDate 2022
url http://eprints.utm.my/103473/
http://dx.doi.org/10.1016/j.coche.2021.100729
_version_ 1783876368156590080
score 13.211869

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