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Characterization of titanium ceramic composite for bone implants applications

Bone implants are widely used to restore bone loss due to several factors including but not limited to osteoporosis, osteoarthritis and road injuries. Current bone implant materials restore mechanical stability but suffer from a lack of osteointegration and will need to be replaced after long term u...

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Main Authors:	Shanmuganantha, Lohashenpahan, Aslam Khan, Muhammad Umar, Sulong, Abu Bakar, Ramlie, Mohd. Ikram, Baharudin, Azmi, Muhamad Ariffin, Hisam, Abd. Razak, Saiful Izwan, Ng, Min Hwei
Format:	Article
Language:	English
Published:	Elsevier Ltd 2022
Subjects:	TP Chemical technology
Online Access:	http://eprints.utm.my/id/eprint/101352/1/SaifulIzwan2022_CharacterizationofTitaniumCeramicCompositeforBone.pdf http://eprints.utm.my/id/eprint/101352/ http://dx.doi.org/10.1016/j.ceramint.2022.04.140
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spelling	my.utm.1013522023-06-08T09:48:57Z http://eprints.utm.my/id/eprint/101352/ Characterization of titanium ceramic composite for bone implants applications Shanmuganantha, Lohashenpahan Aslam Khan, Muhammad Umar Sulong, Abu Bakar Ramlie, Mohd. Ikram Baharudin, Azmi Muhamad Ariffin, Hisam Abd. Razak, Saiful Izwan Ng, Min Hwei TP Chemical technology Bone implants are widely used to restore bone loss due to several factors including but not limited to osteoporosis, osteoarthritis and road injuries. Current bone implant materials restore mechanical stability but suffer from a lack of osteointegration and will need to be replaced after long term use. To circumvent this, tissue engineering which capitalizes on the use of cells, biochemical factors and biodegradable materials aim to develop a biological substitute that restores, maintain or improve tissue functions. Central to the improvement of the tissue function and its stability through the implant relies on its interaction with the host tissue. Hence, a bioactive implant that promotes osteointegration is more desirable than an inert implant. In this study, metal-ceramic composites are explored for their suitability to be used as bone implants in the future. Fabrication of the composite was optimized using hot press compression and vacuum sintering method. Data presented include physicochemical characteristics of titanium-hydroxyapatite and titanium-wollastonite analyzed via SEM, FTIR, XRD, 3D laser microscopy and mechanical test. Evidence of material biocompatibility with primary human osteoprogenitor cells is also provided. Both titanium hydroxyapatite and titanium wollastonite possess the potential as the future of metal-ceramic composites as they possess the bioactivity of ceramic while still maintaining its core titanium body as a source of strength. Elsevier Ltd 2022 Article PeerReviewed application/pdf en http://eprints.utm.my/id/eprint/101352/1/SaifulIzwan2022_CharacterizationofTitaniumCeramicCompositeforBone.pdf Shanmuganantha, Lohashenpahan and Aslam Khan, Muhammad Umar and Sulong, Abu Bakar and Ramlie, Mohd. Ikram and Baharudin, Azmi and Muhamad Ariffin, Hisam and Abd. Razak, Saiful Izwan and Ng, Min Hwei (2022) Characterization of titanium ceramic composite for bone implants applications. Ceramics International, 48 (16). pp. 22808-22819. ISSN 0272-8842 http://dx.doi.org/10.1016/j.ceramint.2022.04.140 DOI : 10.1016/j.ceramint.2022.04.140
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Shanmuganantha, Lohashenpahan Aslam Khan, Muhammad Umar Sulong, Abu Bakar Ramlie, Mohd. Ikram Baharudin, Azmi Muhamad Ariffin, Hisam Abd. Razak, Saiful Izwan Ng, Min Hwei Characterization of titanium ceramic composite for bone implants applications
description	Bone implants are widely used to restore bone loss due to several factors including but not limited to osteoporosis, osteoarthritis and road injuries. Current bone implant materials restore mechanical stability but suffer from a lack of osteointegration and will need to be replaced after long term use. To circumvent this, tissue engineering which capitalizes on the use of cells, biochemical factors and biodegradable materials aim to develop a biological substitute that restores, maintain or improve tissue functions. Central to the improvement of the tissue function and its stability through the implant relies on its interaction with the host tissue. Hence, a bioactive implant that promotes osteointegration is more desirable than an inert implant. In this study, metal-ceramic composites are explored for their suitability to be used as bone implants in the future. Fabrication of the composite was optimized using hot press compression and vacuum sintering method. Data presented include physicochemical characteristics of titanium-hydroxyapatite and titanium-wollastonite analyzed via SEM, FTIR, XRD, 3D laser microscopy and mechanical test. Evidence of material biocompatibility with primary human osteoprogenitor cells is also provided. Both titanium hydroxyapatite and titanium wollastonite possess the potential as the future of metal-ceramic composites as they possess the bioactivity of ceramic while still maintaining its core titanium body as a source of strength.
format	Article
author	Shanmuganantha, Lohashenpahan Aslam Khan, Muhammad Umar Sulong, Abu Bakar Ramlie, Mohd. Ikram Baharudin, Azmi Muhamad Ariffin, Hisam Abd. Razak, Saiful Izwan Ng, Min Hwei
author_facet	Shanmuganantha, Lohashenpahan Aslam Khan, Muhammad Umar Sulong, Abu Bakar Ramlie, Mohd. Ikram Baharudin, Azmi Muhamad Ariffin, Hisam Abd. Razak, Saiful Izwan Ng, Min Hwei
author_sort	Shanmuganantha, Lohashenpahan
title	Characterization of titanium ceramic composite for bone implants applications
title_short	Characterization of titanium ceramic composite for bone implants applications
title_full	Characterization of titanium ceramic composite for bone implants applications
title_fullStr	Characterization of titanium ceramic composite for bone implants applications
title_full_unstemmed	Characterization of titanium ceramic composite for bone implants applications
title_sort	characterization of titanium ceramic composite for bone implants applications
publisher	Elsevier Ltd
publishDate	2022
url	http://eprints.utm.my/id/eprint/101352/1/SaifulIzwan2022_CharacterizationofTitaniumCeramicCompositeforBone.pdf http://eprints.utm.my/id/eprint/101352/ http://dx.doi.org/10.1016/j.ceramint.2022.04.140
_version_	1769842042535411712
score	13.211869

Characterization of titanium ceramic composite for bone implants applications

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