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Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application

Calcium phosphate (CaP) usually been used for bone implant application due to the similarity mineral in natural bone and it is bioactive and biocompatible material. However, CaP has low mechanical strength under load bearing condition and limited on certain application only. Therefore, sodium algina...

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Main Author: Mustaffa, Nor Azimah
Format: Thesis
Language:English
English
English
Published: 2018
Subjects:
R Medicine (General)
R856-857 Biomedical engineering. Electronics. Instrumentation
Online Access:http://eprints.uthm.edu.my/7547/1/24p%20MOHAMAD%20HELMI%20MD%20ANSARI.pdf
http://eprints.uthm.edu.my/7547/2/MOHAMAD%20HELMI%20MD%20ANSARI%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/7547/3/MOHAMAD%20HELMI%20MD%20ANSARI%20WATERMARK.pdf
http://eprints.uthm.edu.my/7547/
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spelling my.uthm.eprints.75472022-08-21T01:44:13Z http://eprints.uthm.edu.my/7547/ Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application Mustaffa, Nor Azimah R Medicine (General) R856-857 Biomedical engineering. Electronics. Instrumentation Calcium phosphate (CaP) usually been used for bone implant application due to the similarity mineral in natural bone and it is bioactive and biocompatible material. However, CaP has low mechanical strength under load bearing condition and limited on certain application only. Therefore, sodium alginate (SA), a natural polymer is combined with CaP and doped with magnesium (Mg) to improve the properties of the CaP. CaP/SA biocomposite was successfully prepared by using precipitation method with different ratio of CaP/SA (I 00/0, 99/1, 97/3, 95/5, 90/10, and 80/20). 95/5 ratio of CaP/SA which the optimum properties of density, hardness, and microstructure analysis was selected to doped with Mg. The composite was then doped with different weight percentage of Mg (0 wt%, 1.0 wt%, 1 .5 wt%, and 2.0 wt%) by using similar method. From FTIR analysis, the addition of Mg in CaP was observed decreasing the phosphate group intensity due to substitution of Mg in CaP that also supported in XRD analysis where new phase was fonned in Mg doping that belongs to Mg-whitlockite (Ca 2. 71 Mg0.29(PO4h. Fmthermore, the addition of SA and Mg was confim1ed by EDS analysis where the mass percentage of these elements were increased as increasing the SA and Mg content. Microstructure from SEM has shown fonnation small and large grain with average grain size obtained 2.61 2018-04 Thesis NonPeerReviewed text en http://eprints.uthm.edu.my/7547/1/24p%20MOHAMAD%20HELMI%20MD%20ANSARI.pdf text en http://eprints.uthm.edu.my/7547/2/MOHAMAD%20HELMI%20MD%20ANSARI%20COPYRIGHT%20DECLARATION.pdf text en http://eprints.uthm.edu.my/7547/3/MOHAMAD%20HELMI%20MD%20ANSARI%20WATERMARK.pdf Mustaffa, Nor Azimah (2018) Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application. Masters thesis, Universiti Tun Hussein Onn Malaysia.
institution Universiti Tun Hussein Onn Malaysia
building UTHM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tun Hussein Onn Malaysia
content_source UTHM Institutional Repository
url_provider http://eprints.uthm.edu.my/
language English
English
English
topic R Medicine (General)
R856-857 Biomedical engineering. Electronics. Instrumentation
spellingShingle R Medicine (General)
R856-857 Biomedical engineering. Electronics. Instrumentation
Mustaffa, Nor Azimah
Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
description Calcium phosphate (CaP) usually been used for bone implant application due to the similarity mineral in natural bone and it is bioactive and biocompatible material. However, CaP has low mechanical strength under load bearing condition and limited on certain application only. Therefore, sodium alginate (SA), a natural polymer is combined with CaP and doped with magnesium (Mg) to improve the properties of the CaP. CaP/SA biocomposite was successfully prepared by using precipitation method with different ratio of CaP/SA (I 00/0, 99/1, 97/3, 95/5, 90/10, and 80/20). 95/5 ratio of CaP/SA which the optimum properties of density, hardness, and microstructure analysis was selected to doped with Mg. The composite was then doped with different weight percentage of Mg (0 wt%, 1.0 wt%, 1 .5 wt%, and 2.0 wt%) by using similar method. From FTIR analysis, the addition of Mg in CaP was observed decreasing the phosphate group intensity due to substitution of Mg in CaP that also supported in XRD analysis where new phase was fonned in Mg doping that belongs to Mg-whitlockite (Ca 2. 71 Mg0.29(PO4h. Fmthermore, the addition of SA and Mg was confim1ed by EDS analysis where the mass percentage of these elements were increased as increasing the SA and Mg content. Microstructure from SEM has shown fonnation small and large grain with average grain size obtained 2.61
format Thesis
author Mustaffa, Nor Azimah
author_facet Mustaffa, Nor Azimah
author_sort Mustaffa, Nor Azimah
title Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
title_short Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
title_full Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
title_fullStr Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
title_full_unstemmed Magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
title_sort magnesium doped calcium phosphate/sodium alginate biocomposite for bone implant application
publishDate 2018
url http://eprints.uthm.edu.my/7547/1/24p%20MOHAMAD%20HELMI%20MD%20ANSARI.pdf
http://eprints.uthm.edu.my/7547/2/MOHAMAD%20HELMI%20MD%20ANSARI%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/7547/3/MOHAMAD%20HELMI%20MD%20ANSARI%20WATERMARK.pdf
http://eprints.uthm.edu.my/7547/
_version_ 1743109098128277504
score 13.211869

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