Cover Image

A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective

Cellulose acetate (CA) is a remarkable biomaterial most extensively used in biomedical applications due to their properties. This review highlighted the synthesis and chemical structure of CA polymer as well as focused on the mechanical, chemical, thermal, biocompatible, and biodegradable properties...

Full description

Saved in:
Bibliographic Details
Main Authors: Wsoo, Mohammed Ahmad, Shahir, Shafinaz, Mohd Bohari, Siti Pauliena, Mat Nayan, Nadirul Hasraf, Abd Razak, Saiful Izwan
Format: Article
Language:English
Published: Elsevier 2020
Subjects:
QD Chemistry
Online Access:http://eprints.uthm.edu.my/6818/1/AJ%202020%20%28431%29.pdf
http://eprints.uthm.edu.my/6818/
https://doi.org/10.1016/j.carres.2020.107978
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uthm.eprints.6818
record_format eprints
spelling my.uthm.eprints.68182022-03-28T01:18:40Z http://eprints.uthm.edu.my/6818/ A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective Wsoo, Mohammed Ahmad Shahir, Shafinaz Mohd Bohari, Siti Pauliena Mat Nayan, Nadirul Hasraf Abd Razak, Saiful Izwan QD Chemistry Cellulose acetate (CA) is a remarkable biomaterial most extensively used in biomedical applications due to their properties. This review highlighted the synthesis and chemical structure of CA polymer as well as focused on the mechanical, chemical, thermal, biocompatible, and biodegradable properties of electrospun CA nanofibers. These properties are essential in the evaluation of the CA nanofibers and provide information as a reference for the further utilization and improvement of CA nanofibers. Moreover, we have summarized the use of electrospun CA nanofibers in the drug delivery system as a carrier for drugs and classify them according to the drug class, including anti-inflammatory, anticancer, antioxidant, antimicrobial agents, vitamins and amino acids. Our review has been concluded that CA nanofibers cannot wholly be biodegraded within the human body due to the absence of cellulase enzyme but degraded by microorganisms. Hence, the biodegradation of CA nanofibers in vivo has addressed as a critical challenge. Elsevier 2020 Article PeerReviewed text en http://eprints.uthm.edu.my/6818/1/AJ%202020%20%28431%29.pdf Wsoo, Mohammed Ahmad and Shahir, Shafinaz and Mohd Bohari, Siti Pauliena and Mat Nayan, Nadirul Hasraf and Abd Razak, Saiful Izwan (2020) A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective. Carbohydrate Research, 491. pp. 1-12. ISSN 0008-6215 https://doi.org/10.1016/j.carres.2020.107978
institution Universiti Tun Hussein Onn Malaysia
building UTHM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tun Hussein Onn Malaysia
content_source UTHM Institutional Repository
url_provider http://eprints.uthm.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Wsoo, Mohammed Ahmad
Shahir, Shafinaz
Mohd Bohari, Siti Pauliena
Mat Nayan, Nadirul Hasraf
Abd Razak, Saiful Izwan
A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
description Cellulose acetate (CA) is a remarkable biomaterial most extensively used in biomedical applications due to their properties. This review highlighted the synthesis and chemical structure of CA polymer as well as focused on the mechanical, chemical, thermal, biocompatible, and biodegradable properties of electrospun CA nanofibers. These properties are essential in the evaluation of the CA nanofibers and provide information as a reference for the further utilization and improvement of CA nanofibers. Moreover, we have summarized the use of electrospun CA nanofibers in the drug delivery system as a carrier for drugs and classify them according to the drug class, including anti-inflammatory, anticancer, antioxidant, antimicrobial agents, vitamins and amino acids. Our review has been concluded that CA nanofibers cannot wholly be biodegraded within the human body due to the absence of cellulase enzyme but degraded by microorganisms. Hence, the biodegradation of CA nanofibers in vivo has addressed as a critical challenge.
format Article
author Wsoo, Mohammed Ahmad
Shahir, Shafinaz
Mohd Bohari, Siti Pauliena
Mat Nayan, Nadirul Hasraf
Abd Razak, Saiful Izwan
author_facet Wsoo, Mohammed Ahmad
Shahir, Shafinaz
Mohd Bohari, Siti Pauliena
Mat Nayan, Nadirul Hasraf
Abd Razak, Saiful Izwan
author_sort Wsoo, Mohammed Ahmad
title A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
title_short A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
title_full A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
title_fullStr A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
title_full_unstemmed A review on the properties of electrospun cellulose acetate and its application in drug delivery systems: A new perspective
title_sort review on the properties of electrospun cellulose acetate and its application in drug delivery systems: a new perspective
publisher Elsevier
publishDate 2020
url http://eprints.uthm.edu.my/6818/1/AJ%202020%20%28431%29.pdf
http://eprints.uthm.edu.my/6818/
https://doi.org/10.1016/j.carres.2020.107978
_version_ 1738581539082469376
score 13.211869

Similar Items