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Molecular docking analysis of 6-paradol, zingerone and zerumbone against human Estrogen Receptor Alpha (ERɑ)

Molecular docking was done to assess the binding affinity of 6-paradol (6PRD), Zingerone (ZGR) and Zerumbone (ZRB) ligand-ERα complex in comparison to Hydroxytamoxifen (HTMX). Docking results showed that Glu353 and Arg394 active residues forms hydrogen bonding with 6PRD and ZGR. Glu353, Leu387 and A...

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Bibliographic Details
Main Authors: Sharif, Faez, Azirudin, Athirah, Saedudin, RD Rohmat, Mohd Yunus, Afdzal, Abdul Hamid, Azzmer Azzar, Kasim, Shahreen
Format: Article
Language:English
Published: Penerbit UTHM 2018
Subjects:
TP248.13-248.65 Biotechnology
Online Access:http://eprints.uthm.edu.my/3644/1/AJ%202018%20%28706%29%20Molecular%20docking%20analysis%20of%206-paradol%2C%20zingerone%20and%20zerumbone%20against%20human%20Estrogen%20Receptor%20Alpha%20%28ER%C9%91%29.pdf
http://eprints.uthm.edu.my/3644/
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http://eprints.uthm.edu.my/3644/1/AJ%202018%20%28706%29%20Molecular%20docking%20analysis%20of%206-paradol%2C%20zingerone%20and%20zerumbone%20against%20human%20Estrogen%20Receptor%20Alpha%20%28ER%C9%91%29.pdf
http://eprints.uthm.edu.my/3644/

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