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Sweat analysis for urea sensing: Trends and challenges

With increasing population there is a rise in pathological diseases that the healthcare facilities are grappling with. Sweat-based wearable technologies for continuous monitoring have overcome the demerits associated with sweat sampling and sensing. Hence, sweat as an alternative biofluid holds grea...

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Main Authors: Narayanamurthy, Vigneswaran, Abhishek Shankar, Futane, Senthil, Mallika, Srinivasan, Arthi, Ramakrishnan, Kalpana
Format: Article
Language:English
Published: Royal Society of Chemistry 2023
Online Access:http://eprints.utem.edu.my/id/eprint/28135/2/0263111032024113257.pdf
http://eprints.utem.edu.my/id/eprint/28135/
https://pubs.rsc.org/en/content/articlelanding/2023/ay/d3ay01089a
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spelling my.utem.eprints.281352025-01-06T10:58:05Z http://eprints.utem.edu.my/id/eprint/28135/ Sweat analysis for urea sensing: Trends and challenges Narayanamurthy, Vigneswaran Abhishek Shankar, Futane Senthil, Mallika Srinivasan, Arthi Ramakrishnan, Kalpana With increasing population there is a rise in pathological diseases that the healthcare facilities are grappling with. Sweat-based wearable technologies for continuous monitoring have overcome the demerits associated with sweat sampling and sensing. Hence, sweat as an alternative biofluid holds great promise for the quantification of a host of biomarkers and understanding the functioning of the body, thereby deducing ailments quickly and economically. This comprehensive review accounts for recent advances in sweat-based LOCs (Lab-On-Chips), which are a likely alternative to the existing blood-urea sample testing that is invasive and time-consuming. The present review is focused on the advancements in sweat-based Lab-On-Chips (LOCs) as an alternative to invasive and time-consuming blood-urea sample testing. In addition, different sweat collection methods (direct skin, near skin and microfluidic) and their mechanism for urea sensing are explained in detail. The mechanism of urea in biofluids in protein metabolism, balancing nitrogen levels and a crucial factor of kidney function is described. In the end, research and technological advancements are explained to address current challenges and enable its widespread implementation. Royal Society of Chemistry 2023 Article PeerReviewed text en http://eprints.utem.edu.my/id/eprint/28135/2/0263111032024113257.pdf Narayanamurthy, Vigneswaran and Abhishek Shankar, Futane and Senthil, Mallika and Srinivasan, Arthi and Ramakrishnan, Kalpana (2023) Sweat analysis for urea sensing: Trends and challenges. Analytical Methods, 15 (35). pp. 4405-4426. ISSN 1759-9679 https://pubs.rsc.org/en/content/articlelanding/2023/ay/d3ay01089a
institution Universiti Teknikal Malaysia Melaka
building UTEM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknikal Malaysia Melaka
content_source UTEM Institutional Repository
url_provider http://eprints.utem.edu.my/
language English
description With increasing population there is a rise in pathological diseases that the healthcare facilities are grappling with. Sweat-based wearable technologies for continuous monitoring have overcome the demerits associated with sweat sampling and sensing. Hence, sweat as an alternative biofluid holds great promise for the quantification of a host of biomarkers and understanding the functioning of the body, thereby deducing ailments quickly and economically. This comprehensive review accounts for recent advances in sweat-based LOCs (Lab-On-Chips), which are a likely alternative to the existing blood-urea sample testing that is invasive and time-consuming. The present review is focused on the advancements in sweat-based Lab-On-Chips (LOCs) as an alternative to invasive and time-consuming blood-urea sample testing. In addition, different sweat collection methods (direct skin, near skin and microfluidic) and their mechanism for urea sensing are explained in detail. The mechanism of urea in biofluids in protein metabolism, balancing nitrogen levels and a crucial factor of kidney function is described. In the end, research and technological advancements are explained to address current challenges and enable its widespread implementation.
format Article
author Narayanamurthy, Vigneswaran
Abhishek Shankar, Futane
Senthil, Mallika
Srinivasan, Arthi
Ramakrishnan, Kalpana
spellingShingle Narayanamurthy, Vigneswaran
Abhishek Shankar, Futane
Senthil, Mallika
Srinivasan, Arthi
Ramakrishnan, Kalpana
Sweat analysis for urea sensing: Trends and challenges
author_facet Narayanamurthy, Vigneswaran
Abhishek Shankar, Futane
Senthil, Mallika
Srinivasan, Arthi
Ramakrishnan, Kalpana
author_sort Narayanamurthy, Vigneswaran
title Sweat analysis for urea sensing: Trends and challenges
title_short Sweat analysis for urea sensing: Trends and challenges
title_full Sweat analysis for urea sensing: Trends and challenges
title_fullStr Sweat analysis for urea sensing: Trends and challenges
title_full_unstemmed Sweat analysis for urea sensing: Trends and challenges
title_sort sweat analysis for urea sensing: trends and challenges
publisher Royal Society of Chemistry
publishDate 2023
url http://eprints.utem.edu.my/id/eprint/28135/2/0263111032024113257.pdf
http://eprints.utem.edu.my/id/eprint/28135/
https://pubs.rsc.org/en/content/articlelanding/2023/ay/d3ay01089a
_version_ 1821007584042156032
score 13.232414

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