Cover Image

Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm

Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S Typhi). During infection the bacteria forms biofilm in the gallbladder to protect itself from the harsh environment of the host. Biofilm formation has been associated with inc...

Full description

Saved in:
Bibliographic Details
Main Author: Jason, Chin Khee Chian
Format: Thesis
Language:English
Published: 2018
Subjects:
QR75-99.5 Bacteria
Online Access:http://eprints.usm.my/61989/1/Transcriptome%20study%20of%20salmonella%20cut.pdf
http://eprints.usm.my/61989/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.usm.eprints.61989
record_format eprints
spelling my.usm.eprints.61989 http://eprints.usm.my/61989/ Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm Jason, Chin Khee Chian QR75-99.5 Bacteria Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S Typhi). During infection the bacteria forms biofilm in the gallbladder to protect itself from the harsh environment of the host. Biofilm formation has been associated with increased resistance towards antibiotics and the host immune system, and promotes bacterial persistence. However, the mechanism of biofilm formation is unknown. High-throughput sequencing using the Illumina HiSeq 2500 platform was performed to study the transcriptome of S. Typhi planktonic, intermediate and mature biofilm cells to identify the genes involved in biofilm formation and to postulate the mechanism of action. Planktonic S. 2018-08 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61989/1/Transcriptome%20study%20of%20salmonella%20cut.pdf Jason, Chin Khee Chian (2018) Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QR75-99.5 Bacteria
spellingShingle QR75-99.5 Bacteria
Jason, Chin Khee Chian
Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
description Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S Typhi). During infection the bacteria forms biofilm in the gallbladder to protect itself from the harsh environment of the host. Biofilm formation has been associated with increased resistance towards antibiotics and the host immune system, and promotes bacterial persistence. However, the mechanism of biofilm formation is unknown. High-throughput sequencing using the Illumina HiSeq 2500 platform was performed to study the transcriptome of S. Typhi planktonic, intermediate and mature biofilm cells to identify the genes involved in biofilm formation and to postulate the mechanism of action. Planktonic S.
format Thesis
author Jason, Chin Khee Chian
author_facet Jason, Chin Khee Chian
author_sort Jason, Chin Khee Chian
title Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
title_short Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
title_full Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
title_fullStr Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
title_full_unstemmed Transcriptome Study Of Salmonella Enterica Subspecies Enterica Serovar Typhi Biofilm
title_sort transcriptome study of salmonella enterica subspecies enterica serovar typhi biofilm
publishDate 2018
url http://eprints.usm.my/61989/1/Transcriptome%20study%20of%20salmonella%20cut.pdf
http://eprints.usm.my/61989/
_version_ 1825807291790655488
score 13.244413

Similar Items