In Vitro Anti Cancer Properties Of Thiadiazole Coumarin Derivatives Against Colon Cancer
Thiadiazole coumarin derivatives have been shown to be promising anti-cancer agents. In this study, five different thiadoazole coumarin derivatives (TCDs) were studied for their anticancer activity towards colorectal, breast and lung carcinoma. The TCDs {(OCH3-TC 1), (H3CO-TC 2), (H3CO-TC 3), (Br...
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| Format: | Thesis |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://eprints.usm.my/61960/1/In%20vitro%20anti%20cancer%20properties%20cut.pdf http://eprints.usm.my/61960/ |
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| Summary: | Thiadiazole coumarin derivatives have been shown to be promising anti-cancer
agents. In this study, five different thiadoazole coumarin derivatives (TCDs) were
studied for their anticancer activity towards colorectal, breast and lung carcinoma. The
TCDs {(OCH3-TC 1), (H3CO-TC 2), (H3CO-TC 3), (Br-TC 4), & (OH-TC)} are
different in their structures. The compounds were tested for two important pathways of
carcinogenesis namely angiogenesis and apoptosis. Angiogenesis is a process of new
blood vessel development which is crucial for neoplastic tissues to obtain nourishment
for their growth and metastasis. |
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