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A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients

The incidence of hyperglycaemia, hypertension and hyperlipidaemia (3Hs) have been prevalent in many developed and developing countries. Sacha Inchi oil (SIO) is a rich source of plant-based omega-3, 6, and 9 polyunsaturated fatty acids with promising health effects. However, the effects of SIO as c...

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Main Author: Mhd Rodzi, Nur Anis Raihana
Format: Thesis
Language:English
Published: 2024
Subjects:
T11.95-12.5 Industrial directories
Online Access:http://eprints.usm.my/61457/1/NUR%20ANIS%20RAIHANA%20MHD%20RODZI%20-%20TESIS%20cut.pdf
http://eprints.usm.my/61457/
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spelling my.usm.eprints.61457 http://eprints.usm.my/61457/ A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients Mhd Rodzi, Nur Anis Raihana T11.95-12.5 Industrial directories The incidence of hyperglycaemia, hypertension and hyperlipidaemia (3Hs) have been prevalent in many developed and developing countries. Sacha Inchi oil (SIO) is a rich source of plant-based omega-3, 6, and 9 polyunsaturated fatty acids with promising health effects. However, the effects of SIO as complementary medicine among the 3Hs individuals are narrowly investigated. The present randomised, doubleblind, placebo-controlled human clinical trial aimed to explore the effects of SIO supplementation on (1) glycaemic control; (2) BPs; (3) lipid profiles; (4) inflammatory status; (5) oxidative stress; (6) circulating arterial calcification biomarkers; (7) anthropometry measurements; (8) quality of life; (9) mental health status; and (10) compliancy and tolerability among 3Hs patients. Fifty-four (n=54) 3Hs patients were recruited from Specialist Day Care Clinic, Pusat Perubatan USM Bertam, and randomised into two groups: the SIO group (n=27) (received 1000mg of SIO soft gel per day) or placebo group (n=27) (received 1000mg corn oil soft gel for 12 weeks). Fasting blood samples were collected at baseline and post week-12 to assess clinical and laboratory biochemical markers. 2024-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61457/1/NUR%20ANIS%20RAIHANA%20MHD%20RODZI%20-%20TESIS%20cut.pdf Mhd Rodzi, Nur Anis Raihana (2024) A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic T11.95-12.5 Industrial directories
spellingShingle T11.95-12.5 Industrial directories
Mhd Rodzi, Nur Anis Raihana
A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
description The incidence of hyperglycaemia, hypertension and hyperlipidaemia (3Hs) have been prevalent in many developed and developing countries. Sacha Inchi oil (SIO) is a rich source of plant-based omega-3, 6, and 9 polyunsaturated fatty acids with promising health effects. However, the effects of SIO as complementary medicine among the 3Hs individuals are narrowly investigated. The present randomised, doubleblind, placebo-controlled human clinical trial aimed to explore the effects of SIO supplementation on (1) glycaemic control; (2) BPs; (3) lipid profiles; (4) inflammatory status; (5) oxidative stress; (6) circulating arterial calcification biomarkers; (7) anthropometry measurements; (8) quality of life; (9) mental health status; and (10) compliancy and tolerability among 3Hs patients. Fifty-four (n=54) 3Hs patients were recruited from Specialist Day Care Clinic, Pusat Perubatan USM Bertam, and randomised into two groups: the SIO group (n=27) (received 1000mg of SIO soft gel per day) or placebo group (n=27) (received 1000mg corn oil soft gel for 12 weeks). Fasting blood samples were collected at baseline and post week-12 to assess clinical and laboratory biochemical markers.
format Thesis
author Mhd Rodzi, Nur Anis Raihana
author_facet Mhd Rodzi, Nur Anis Raihana
author_sort Mhd Rodzi, Nur Anis Raihana
title A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
title_short A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
title_full A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
title_fullStr A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
title_full_unstemmed A Randomized, Double Blind, Placebo-Controlled Human Clinical Trial On The Effects Of Sacha Inchi (Plukenetia Volubilis L.) Oil Supplementation In Hyperglycaemia, Hypertension And Hyperlipidaemia Patients
title_sort randomized, double blind, placebo-controlled human clinical trial on the effects of sacha inchi (plukenetia volubilis l.) oil supplementation in hyperglycaemia, hypertension and hyperlipidaemia patients
publishDate 2024
url http://eprints.usm.my/61457/1/NUR%20ANIS%20RAIHANA%20MHD%20RODZI%20-%20TESIS%20cut.pdf
http://eprints.usm.my/61457/
_version_ 1823273892831035392
score 13.239859

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