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Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis

Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximatel...

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Main Author: Hassan, Nur Hassanah Mohd
Format: Thesis
Language:English
Published: 2023
Subjects:
T1-995 Technology(General)
Online Access:http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf
http://eprints.usm.my/61321/
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spelling my.usm.eprints.61321 http://eprints.usm.my/61321/ Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis Hassan, Nur Hassanah Mohd T1-995 Technology(General) Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximately 613.9 million cases mostly in tropical countries. Human infection occurs when the infective filariform S. stercoralis larvae in contaminated soil penetrate the intact skin through direct contact, travel to the mouth through bloodstream before it gets swallowed and resides in the gut. In the gut, female adult larvae produce eggs parthenogenetically, continuing their life cycle without having to leave the host’s body through a process called autoinfection. In general, the post-infection symptoms vary in two different ways. In immunocompetent individuals, hosts usually exhibit minimal to no symptoms (asymptomatic) and causes a life-long infection whereas in immunosuppressed individuals, unchecked infection is highly inclinative towards developing hyperinfection syndrome, an event where the larvae over-proliferate and disseminate to organs including the lung, liver, and brain. 2023-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf Hassan, Nur Hassanah Mohd (2023) Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis. Masters thesis, Perpustakaan Hamzah Sendut.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic T1-995 Technology(General)
spellingShingle T1-995 Technology(General)
Hassan, Nur Hassanah Mohd
Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
description Strongyloides stercoralis is a human-pathogenic nematode with a unique ability to autoinfect causing a parasitic disease called strongyloidiasis. Although listed as one of the neglected tropical diseases by World Health Organisation (WHO), the infection has a worldwide distribution with approximately 613.9 million cases mostly in tropical countries. Human infection occurs when the infective filariform S. stercoralis larvae in contaminated soil penetrate the intact skin through direct contact, travel to the mouth through bloodstream before it gets swallowed and resides in the gut. In the gut, female adult larvae produce eggs parthenogenetically, continuing their life cycle without having to leave the host’s body through a process called autoinfection. In general, the post-infection symptoms vary in two different ways. In immunocompetent individuals, hosts usually exhibit minimal to no symptoms (asymptomatic) and causes a life-long infection whereas in immunosuppressed individuals, unchecked infection is highly inclinative towards developing hyperinfection syndrome, an event where the larvae over-proliferate and disseminate to organs including the lung, liver, and brain.
format Thesis
author Hassan, Nur Hassanah Mohd
author_facet Hassan, Nur Hassanah Mohd
author_sort Hassan, Nur Hassanah Mohd
title Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_short Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_full Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_fullStr Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_full_unstemmed Optimizing The Production Of Short-Peptide Tagged Ss3A Recombinant Protein As A Potential Serological Biomarker For Strongyloidiasis
title_sort optimizing the production of short-peptide tagged ss3a recombinant protein as a potential serological biomarker for strongyloidiasis
publishDate 2023
url http://eprints.usm.my/61321/1/24%20Pages%20from%20NUR%20HASSANAH%20BINTI%20MOHD%20HASSAN.pdf
http://eprints.usm.my/61321/
_version_ 1814048437615722496
score 13.211869

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